Evidence map›Paper›PMID 33376204›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Cooperative formation of porous silica and peptides on the prebiotic Earth.

Alexandra Navrotsky, Richard Hervig, James Lyons, Dong-Kyun Seo, Everett Shock, Albert Voskanyan

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Concomitant formation of protocells and prebiotic compounds under a plausible early Earth atmosphere.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alexandra NavrotskyCenter for Materials of the Universe, Arizona State University, Tempe, AZ 85287; alexnav@asu.edu.ORCID 0000-0002-3260-0364
Richard HervigCenter for Materials of the Universe, Arizona State University, Tempe, AZ 85287.ORCID 0000-0001-7892-5423
James LyonsCenter for Materials of the Universe, Arizona State University, Tempe, AZ 85287.
Dong-Kyun SeoCenter for Materials of the Universe, Arizona State University, Tempe, AZ 85287.
Everett ShockCenter for Materials of the Universe, Arizona State University, Tempe, AZ 85287.
Albert VoskanyanCenter for Materials of the Universe, Arizona State University, Tempe, AZ 85287.
Arizona State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern technology has perfected the synthesis of catalysts such as zeolites and mesoporous silicas using organic structure directing agents (SDA) and their industrial use to catalyze a large variety of organic reactions within their pores. We suggest that early in prebiotic evolution, synergistic interplay arose between organic species in aqueous solution and silica formed from rocks by dynamic dissolution-recrystallization. The natural organics, for example, amino acids, small peptides, and fatty acids, acted as SDA for assembly of functional porous silica structures that induced further polymerization of amino acids and peptides, as well as other organic reactions. Positive feedback between synthesis and catalysis in the silica-organic system may have accelerated the early stages of abiotic evolution by increasing the formation of polymerized species.

Indexed as

Amino AcidsCatalysisEarth, PlanetEvolution, ChemicalOrigin of LifePeptidesPolymerizationSilicon DioxideZeolitesAmino AcidsPeptidesSilicon DioxideZeolitespeptide synthesisprebiotic chemistrysilicazeolites

Identifiers

PMID33376204
PMCPMC7812765
OpenAlexW3114167725

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.