Evidence map›Paper›PMID 33376141›Full record

ArticleThe Journal of experimental biology2021

The impact of the gut microbiome on memory and sleep in

Valeria Silva, Angelina Palacios-Muñoz, Zeynep Okray, Karen L Adair, Scott Waddell, Angela E Douglas, John Ewer

Open access · hybridAbstract read
In one paragraph

Article in The Journal of experimental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 42 citations in OpenAlex.

  1. International journal of molecular sciences · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Gut microbiome and host TOR pathway interact to regulate predator-induced aversive memory inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Alzheimer's disease and gut-brain axis:Frontiers in neuroscience · 2025
    Review
  12. Article
  13. Article
  14. Sex Differences in Sociability formicroPublication biology · 2024
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Recent trends in insect gut immunity.Frontiers in immunology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Valeria SilvaInstituto de Neurociencias, and Centro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, Valparaíso 2360102, Chile.ORCID 0000-0003-4598-0973
Angelina Palacios-MuñozInstituto de Neurociencias, and Centro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, Valparaíso 2360102, Chile.
Zeynep OkrayCentre for Neural Circuits & Behaviour, University of Oxford, Oxford OX1 3TA, UK.ORCID 0000-0003-2295-3809
Karen L AdairDepartment of Entomology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-1842-2995
Scott WaddellCentre for Neural Circuits & Behaviour, University of Oxford, Oxford OX1 3TA, UK.ORCID 0000-0003-4503-6229
Angela E DouglasDepartment of Entomology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-5212-6826
John EwerInstituto de Neurociencias, and Centro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, Valparaíso 2360102, Chile john.ewer@uv.cl.ORCID 0000-0002-6806-3628
University of Valparaíso · CLCornell University · USUniversity of Oxford · GB

Funding

The protein nutrition of the symbiotic system between /Drosophila/and its gut micR01GM095372 · NIGMS · CORNELL UNIVERSITY · PI SEARLE, ANGELA E · 2011 to 2019
$2.8M
NIGMS NIH HHS R01 GM095372Wellcome Trust 200846/Z/16/Z
6 · The paper itself

Abstract

The gut microbiome has been proposed to influence diverse behavioral traits of animals, although the experimental evidence is limited and often contradictory. Here, we made use of the tractability of

Indexed as

Drosophila melanogasterGastrointestinal MicrobiomeAnimalsCircadian RhythmDrosophilaMemorySleepAnxietyAxenicBehaviorCircadian rhythmInsectLearningLocomotor activitySleep recovery

Identifiers

PMID33376141
PMCPMC7875489
OpenAlexW3117325545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.