Evidence map›Paper›PMID 33376008›Full record

SynthesisJournal of the Formosan Medical Association = Taiwan yi zhi2021

Clinical and laboratory findings of COVID-19: A systematic review and meta-analysis.

Amar Hassan Khamis, Mohamed Jaber, Aida Azar, Feras AlQahtani, Khaled Bishawi, Ahmed Shanably

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of the Formosan Medical Association = Taiwan yi zhi, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amar Hassan KhamisBiostatistics, Hamdan Bin Mohammed College of Dental Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, P.O Box 505055, Dubai UAE, Building 14, Dubai Healthcare City, United Arab Emirates.
Mohamed JaberClinical Sciences Department, College of Dentistry, Ajman University, P.O Box 346, Ajman, Ajman, United Arab Emirates. Electronic address: mjaber4@hotmail.com.
Aida AzarEpidemiology, College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, P.O Box 505055, Dubai UAE, Building 14, Dubai Healthcare City, United Arab Emirates.
Feras AlQahtaniCollege of Dentistry, Ajman University, United Arab Emirates, P.O Box 346, Ajman, Ajman, United Arab Emirates.
Khaled BishawiCollege of Dentistry, Ajman University, United Arab Emirates, P.O Box 346, Ajman, Ajman, United Arab Emirates.
Ahmed ShanablyCollege of Dentistry, Ajman University, United Arab Emirates, P.O Box 346, Ajman, Ajman, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/purposeThe aim of this study was to systematically review all COVID-19 publications to summarize the clinical features, assess comorbidities, prevalence, and disease outcomes.

methodsIncluded were all COVID-19 published studies between January 1 to July 20, 2020. The random effect model was used to calculate the pooled prevalence and corresponding 95% confidence interval (CI). Publication bias was assessed using the funnel plot for the standard error by logit event.

resultsThe mean age of the patients was 46.8 years (95% CI, 41.0-52.6) and males comprised 54.0% (95% CI, 51.3-56.7). Total co-morbidities prevalence was 29.5% (95% CI, 19.0-36.6), with diabetes mellitus being the most prevalent 13.8% (95% CI, 8.7-21.1), followed by hypertension 11.7% (95% CI, 5.7-22.6), and cardiovascular disease 9.7% (95% CI, 6.5-14.2). The most common clinical manifestations were fever, 82.0% (95% CI, 67.7-90.8), cough 54.3% (95% CI, 45.5-62.9), fatigue 30.2% (95% CI, 23.3-38.1), sputum 28.5% (95% CI, 21.2-37.2), sore throat 21.7% (95% CI, 14.6-31.0), and headache 11.0% (95% CI, 7.9-15.2). The most common COVID-19 serious complications were RNA Anemia 98.2% (95% CI, 96.2-99.2), hospitalization 83.7% (95% CI, 76.0-89.3), bilateral pneumonia 70.9% (95% CI, 58.2-81.0); of those hospitalized 43.5% (95% CI, 24.9-64.2) were discharged. Fatality accounted for 10.5% (95% CI 6.8-16.1).

conclusionPatients infected with COVID-19 coronavirus showed a wide range of clinical presentation with non-specific symptoms.

Indexed as

COVID-19CoughFemaleFeverHumansLaboratoriesMaleMiddle AgedSARS-CoV-2Clinical featuresCOVID-19EpidemicMeta-analysisSARS-CoV-2

Identifiers

PMID33376008
PMCPMC7832677

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.