Evidence map›Paper›PMID 33375792›Full record

ArticleJournal of the American Chemical Society2021

Origin of Free Energy Barriers of Decarboxylation and the Reverse Process of CO

Shaoyuan Zhou, Bach T Nguyen, John P Richard, Ronald Kluger, Jiali Gao

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Shaoyuan ZhouInstitute of Systems and Physical Biology, Shenzhen Bay Laboratory, Shenzhen 581055, China.
Bach T NguyenDepartment of Chemistry and Supercomputing Institute, University of Minnesota, Minneapolis, Minnesota 55455, United States.
John P RichardDepartment of Chemistry, State University of New York at Buffalo, Buffalo, New York 47907, United States.ORCID 0000-0002-0440-2387
Ronald KlugerDepartment of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.ORCID 0000-0002-1749-2094
Jiali GaoInstitute of Systems and Physical Biology, Shenzhen Bay Laboratory, Shenzhen 581055, China.ORCID 0000-0003-0106-7154
University of Minnesota · USJilin University · CNUniversity at Buffalo, State University of New York · USUniversity of Toronto · CA

Funding

BIOMOLECULAR INTERACTIONS AND ENZYMATIC PROCESSESR01GM046736 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI JIALI GAO · 1993 to 2026
$6.5M
Studies on Enzyme Activation and Novel Modes of Inhibition. Administrative Supplement for EquipmentR35GM134881 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI John P Richard · 2020 to 2026
$2.5M
NIGMS NIH HHS R01 GM046736NIGMS NIH HHS R35 GM134881
6 · The paper itself

Abstract

In aqueous solution, biological decarboxylation reactions proceed irreversibly to completion, whereas the reverse carboxylation processes are typically powered by the hydrolysis of ATP. The exchange of the carboxylate of ring-substituted arylacetates with isotope-labeled CO

Indexed as

Carbon DioxideCarboxylic AcidsDecarboxylationDimethylformamideMolecular Dynamics SimulationSolventsThermodynamicsWaterCarbon DioxideCarboxylic AcidsDimethylformamideSolventsWater

Identifiers

PMID33375792
PMCPMC8058934
OpenAlexW3114323188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.