Evidence map›Paper›PMID 33375761›Full record

ArticlePolymers2020

Aligned Nanofiber-Guided Bone Regeneration Barrier Incorporated with Equine Bone-Derived Hydroxyapatite for Alveolar Bone Regeneration.

Jae Woon Lim, Kyoung-Je Jang, Hyunmok Son, Sangbae Park, Jae Eun Kim, Hong Bae Kim, Hoon Seonwoo, Yun-Hoon Choung, Myung Chul Lee, Jong Hoon Chung

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Recent Advances in Scaffolds for Guided Bone Regeneration.Biomimetics (Basel, Switzerland) · 2024
    Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jae Woon LimDepartment of Biosystems Engineering, Seoul National University, Seoul 08826, Korea.
Kyoung-Je JangDivision of Agro-system Engineering, Gyeongsang National University, Jinju 52828, Korea.
Hyunmok SonDepartment of Biosystems Engineering, Seoul National University, Seoul 08826, Korea.
Sangbae ParkDepartment of Biosystems Engineering, Seoul National University, Seoul 08826, Korea.ORCID 0000-0003-0559-4840
Jae Eun KimDepartment of Biosystems Engineering, Seoul National University, Seoul 08826, Korea.
Hong Bae KimDepartment of Biosystems Engineering, Seoul National University, Seoul 08826, Korea.
Hoon SeonwooDepartment of Industrial Machinery Engineering, College of Life Science and Natural Resources, Sunchon National University, Sunchon 57922, Korea.
Yun-Hoon ChoungDepartment of Otolaryngology, Ajou University School of Medicine, Suwon 16499, Korea.
Myung Chul LeeDepartment of Biosystems Engineering, Seoul National University, Seoul 08826, Korea.ORCID 0000-0002-0566-8494
Jong Hoon ChungDepartment of Biosystems Engineering, Seoul National University, Seoul 08826, Korea.ORCID 0000-0003-0711-5655
Seoul National University · KRAjou University · KRGyeongsang National University · KRSunchon National University · KR

Funding

National Research Foundation of Korea NRF-2020R1F1A1067439
6 · The paper itself

Abstract

Post-surgery failure of dental implants due to alveolar bone loss is currently critical, disturbing the quality of life of senior dental patients. To overcome this problem, bioceramic or bone graft material is loaded into the defect. However, connective tissue invasion instead of osteogenic tissue limits bone tissue regeneration. The guided bone regeneration concept was adapted to solve this problem and still has room for improvements, such as biochemical similarity or oriented structure. In this article, an aligned electrospun-guided bone regeneration barrier with xenograft equine bone-derived nano hydroxyapatite (EBNH-RB) was fabricated by electrospinning EBNH/PCL solution on high-speed rotating drum collector and fiber characterization, viability and differentiation enhancing properties of mesenchymal dental pulp stem cell on the barrier was determined. EBNH-RB showed biochemical and structural similarity to natural bone tissue electron microscopy image analysis and x-ray diffractometer analysis, and had a significantly better effect in promoting osteogenesis based on the increased bioceramic content by promoting cell viability, calcium deposition and osteogenic marker expression, suggesting that they can be successfully applied to regenerate alveolar bone as a guided bone regeneration barrier.

Indexed as

equine bonehydroxyapatitenanofiberosteogenesisregeneration barrier

Identifiers

PMID33375761
PMCPMC7796229
OpenAlexW3116341886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.