Evidence map›Paper›PMID 33375687›Full record

ArticleMolecules (Basel, Switzerland)2020

Alkaloids with Anti-Onchocercal Activity from

Smith B Babiaka, Conrad V Simoben, Kennedy O Abuga, James A Mbah, Rajshekhar Karpoormath, Dennis Ongarora, Hannington Mugo, Elvis Monya, Fidelis Cho-Ngwa, Wolfgang Sippl and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Smith B BabiakaDepartment of Chemistry, Faculty of Science, University of Buea, P.O. Box 63, Buea CM-00237, Cameroon.
Conrad V SimobenInstitute for Pharmacy, Martin-Luther-Universität Halle-Wittenberg, Kurt-Mothes-Str. 3, 06120 Halle, Germany.ORCID 0000-0002-5958-6961
Kennedy O AbugaDepartment of Pharmaceutical Chemistry, School of Pharmacy, University of Nairobi, Nairobi P.O. Box 19676-00202, Kenya.
James A MbahDepartment of Chemistry, Faculty of Science, University of Buea, P.O. Box 63, Buea CM-00237, Cameroon.
Rajshekhar KarpoormathDepartment of Pharmaceutical Chemistry, School of Chemistry, University of KwaZulu-Natal, Durban 4001, South Africa.ORCID 0000-0002-1247-5754
Dennis OngaroraDepartment of Pharmaceutical Chemistry, School of Pharmacy, University of Nairobi, Nairobi P.O. Box 19676-00202, Kenya.ORCID 0000-0002-4385-4271
Hannington MugoDepartment of Pharmaceutical Chemistry, School of Pharmacy, University of Nairobi, Nairobi P.O. Box 19676-00202, Kenya.
Elvis MonyaANDI Centre of Excellence for Onchocerciasis Drug Research, Biotechnology Unit, Faculty of Science, University of Buea, P.O. Box 63, Buea CM-00237, Cameroon.
Fidelis Cho-NgwaANDI Centre of Excellence for Onchocerciasis Drug Research, Biotechnology Unit, Faculty of Science, University of Buea, P.O. Box 63, Buea CM-00237, Cameroon.
Wolfgang SipplInstitute for Pharmacy, Martin-Luther-Universität Halle-Wittenberg, Kurt-Mothes-Str. 3, 06120 Halle, Germany.ORCID 0000-0002-5985-9261
E Joel LoveridgeDepartment of Chemistry, Swansea University, Singleton Park, Swansea SA2 8PP, UK.
Fidele Ntie-KangDepartment of Chemistry, Faculty of Science, University of Buea, P.O. Box 63, Buea CM-00237, Cameroon.ORCID 0000-0003-0795-394X

Funding

Alexander von Humboldt-Stiftung FNKDAAD FNK
6 · The paper itself

Abstract

A new iboga-vobasine-type isomeric bisindole alkaloid named voacamine A (

Indexed as

AlkaloidsAnimalsHumansOnchocercaOnchocerciasisVoacangaAlkaloidsalkaloidsanti-onchocercalbisindolesdockinghomology modelingmonoindoles

Identifiers

PMID33375687
PMCPMC7795662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.