Evidence map›Paper›PMID 33375677›Full record

ReviewVaccines2020

Platforms Exploited for SARS-CoV-2 Vaccine Development.

Shilu Mathew, Muhammed Faheem, Neeraja A Hassain, Fatiha M Benslimane, Asmaa A Al Thani, Hassan Zaraket, Hadi M Yassine

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.5field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Humoral responses to the CoronoVac vaccine in healthcare workers.Revista da Sociedade Brasileira de Medicina Tropical · 2023
    Article
  7. A comparison between SARS-CoV-1 and SARS-CoV2: an update on current COVID-19 vaccines.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2022
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Frontiers in tropical diseases · 2021
    Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Shilu MathewBiomedical Research Center, Qatar University, Doha 2173, Qatar.
Muhammed FaheemGenetics & Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Neeraja A HassainDepartment of Biotechnology, Jamal Mohamed College, Tamil Nadu 620020, India.
Fatiha M BenslimaneBiomedical Research Center, Qatar University, Doha 2173, Qatar.ORCID 0000-0003-3792-252X
Asmaa A Al ThaniBiomedical Research Center, Qatar University, Doha 2173, Qatar.
Hassan ZaraketDepartment of Experimental Pathology, Immunology, and Microbiology, Faculty of Medicine, American University of Beirut, Beirut 11-0236, Lebanon.ORCID 0000-0003-3807-6409
Hadi M YassineBiomedical Research Center, Qatar University, Doha 2173, Qatar.ORCID 0000-0001-7592-2788
Qatar University · QAAmerican University of Beirut · LBHospital for Sick Children · CA

Funding

Qatar University QUHI-BRC-20/21-1
6 · The paper itself

Abstract

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the only zoonotic-origin coronavirus (CoV) that has reached the pandemic stage. The virus uses its spike (S) glycoprotein to attach to the host cells and initiate a cascade of events that leads to infection. It has sternly affected public health, economy, education, and social behavior around the world. Several scientific and medical communities have mounted concerted efforts to limit this pandemic and the subsequent wave of viral spread by developing preventative and potential vaccines. So far, no medicine or vaccine has been approved to prevent or treat coronavirus disease 2019 (COVID-19). This review describes the latest advances in the development of SARS-CoV-2 vaccines for humans, mainly focusing on the lead candidates in clinical trials. Moreover, we seek to provide both the advantages and the disadvantages of the leading platforms used in current vaccine development, based on past vaccine delivery efforts for non-SARS CoV-2 infections. We also highlight the population groups who should receive a vaccine against COVID-19 in a timely manner to eradicate the pandemic rapidly.

Indexed as

clinical trialsCovid-19SARS-CoV-2vaccine platformsvaccines

Identifiers

PMID33375677
PMCPMC7824029
OpenAlexW3116829181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.