ArticleJournal of clinical medicine2020
Endoscopic Skull Base Repair Strategy for CSF Leaks Associated with Pneumocephalus.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- A Case of Pneumocephalus on Valsalva Maneuver: A Case Report and Literature Review.The American journal of case reports · 2026Review
- A rare combination of a meningioma and an ethmoidal meningoencephalocele with osteo-dural defect: Diagnostic and therapeutic challenges.Surgical neurology international · 2026Article
- Microscopic endonasal transsphenoidal approach for repair of sellar defect from penetrating trauma during wartime: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Sphenoid sinus hyperpneumatization: anatomical variants, molecular blueprints, and AI-augmented roadmaps for skull base surgery.Frontiers in endocrinology · 2025Review
- Pneumocephalus and Pneumorrhachis Following Titanium Rib Implant: A Case Report and Literature Review.Current medical imaging · 2025Review
- A Comprehensive Analysis of Tobacco Smoking History as a Risk for Outcomes after Endoscopic Transsphenoidal Resection of Pituitary Adenoma.Journal of neurological surgery. Part B, Skull base · 2024Article
- Dural reconstruction with or without a bone graft of paranasal and anterior skullbase malignancies: Retrospective single-center analysis of 11 cases and review of literature.Brain & spine · 2024Article
- Traumatic tension pneumocephalus: a case report and perspective from Indonesia.Frontiers in neurology · 2024Article
- Traumatic tension pneumocephalus: a case report and perspective from Indonesia.Frontiers in neurology · 2024Article
- Transnasal Endoscopic Treatment of Tension Pneumocephalus Caused by Posttraumatic or Iatrogenic Ethmoidal Damage.Case reports in otolaryngology · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCerebrospinal (CSF) fluid leaks with associated pneumocephalus (PNC) represent a condition bearing serious risks for the patient, with little data available in the literature. Reported success rates of endoscopic skull base repair are lower when PNC is associated than in the case of simple CSF leaks. The present study represents an analysis of our experience with endoscopic management of this condition.
methodsRecords of patients with pneumocephalus and associated CSF leaks, who underwent endoscopic skull base repair, were reviewed. Demographics, history, etiology of PNC, size of defect, surgical approach, reconstruction technique and complications were evaluated.
resultsTwenty patients with CSF leaks and PNC underwent endonasal repair by the senior author between 2005 and 2019. Defect size was larger than 15 mm in all cases. All patients presented either worsening of PNC under conservative treatment or tension PNC. First-attempt closure of the defect was successful in all patients (100%), with resolution of the pneumocephalus. One patient developed a synechia in the proximity of the frontal ostium, as a postoperative complication. The mean follow-up was 39 months (range: 15-94 months).
conclusionThe present study represents a proposed argument for earlier endoscopic endonasal treatment in patients presenting CSF leaks and pneumocephalus.
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