Evidence map›Paper›PMID 33375656›Full record

ArticleBiomolecules2020

Bacterial-Derived Plant Protection Metabolite 2,4-Diacetylphloroglucinol: Effects on Bacterial Cells at Inhibitory and Subinhibitory Concentrations.

William T Julian, Anastasia V Vasilchenko, Daniil D Shpindyuk, Darya V Poshvina, Alexey S Vasilchenko

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  5. Review
  6. Article
  7. Article
  8. New Insights intoAntibiotics (Basel, Switzerland) · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Cofunctioning of bacterial exometabolites drives root microbiota establishment.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  15. 2,4-Diacetylphloroglucinol ModulatesJournal of fungi (Basel, Switzerland) · 2022
    Article
  16. Article
  17. Microorganisms · 2022
    Article
  18. Microorganisms · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

William T JulianLaboratory of Antimicrobial Resistance, Institute of Environmental and Agricultural Biology (X-BIO), Tyumen State University, 625003 Tyumen, Russia.
Anastasia V VasilchenkoLaboratory of Antimicrobial Resistance, Institute of Environmental and Agricultural Biology (X-BIO), Tyumen State University, 625003 Tyumen, Russia.
Daniil D ShpindyukLaboratory of Antimicrobial Resistance, Institute of Environmental and Agricultural Biology (X-BIO), Tyumen State University, 625003 Tyumen, Russia.
Darya V PoshvinaLaboratory of Antimicrobial Resistance, Institute of Environmental and Agricultural Biology (X-BIO), Tyumen State University, 625003 Tyumen, Russia.
Alexey S VasilchenkoLaboratory of Antimicrobial Resistance, Institute of Environmental and Agricultural Biology (X-BIO), Tyumen State University, 625003 Tyumen, Russia.ORCID 0000-0001-9970-4881
University of Tyumen · RU

Funding

Russian Science Foundation 19-76-30005
6 · The paper itself

Abstract

2,4-Diacetylphloroglucinol (2,4-DAPG) is a well-known bacterial secondary metabolite, however, its mechanism of inhibitory and subinhibitory action on bacterial cells is still poorly understood. The mechanism of 2,4-DAPG action on model bacterial strains was investigated using fluorescent spectroscopy and the action of the antibiotic was found to involve a rapid increase in membrane permeability that was accompanied by a reduction in its viability in nutrient-poor medium. At the same time, antibacterial action in nutrient-rich medium developed for several hours. Atomic force microscopy demonstrated time-dependent disturbances in the outer membrane of

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsBiofilmsCell Membrane PermeabilityEscherichia coliGene Expression Regulation, BacterialMicroscopy, Atomic ForcePhloroglucinolPseudomonas fluorescensQuorum SensingSecondary MetabolismStaphylococcus aureus2,4-diacetylphloroglucinolAnti-Bacterial AgentsAnti-Infective AgentsPhloroglucinol2,4-diacetylphloroglucinolmembrane permeabilizationPectobacterium carotovorumplant protectionquorum sensingsubinhibitory effects

Identifiers

PMID33375656
PMCPMC7823703
OpenAlexW3114158939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.