ReviewJournal of clinical medicine2020
Comparison of Blood Flow Restriction Training versus Non-Occlusive Training in Patients with Anterior Cruciate Ligament Reconstruction or Knee Osteoarthritis: A Systematic Review.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effectiveness of Blood Flow Restriction on Functionality, Quality of Life and Pain in Patients with Neuromusculoskeletal Pathologies: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- Pooled it
- Effect of Blood Flow Restriction Technique on Delayed Onset Muscle Soreness: A Systematic Review.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Effects of blood flow restriction therapy for lower limb dysfunction in stroke patients: a systematic review and meta-analysis.Frontiers in neurologyPooled it
- The effects of short-term blood flow restriction training on knee function and quality of life in older adults patients with tibial plateau fractures.Scientific reports · 2026Trial
- Walking with blood flow restriction on lower limb muscles post-ACL reconstruction: A within-subject trial.PloS one · 2025Trial
- Effects of Blood Flow Restriction Therapy in Individuals With Knee Osteoarthritis: Overview of Systematic Reviews.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2026Review
- Article
- Blood Flow Restriction Training Prior to and After Anterior Cruciate Ligament Reconstruction: A Scoping Review.Journal of functional morphology and kinesiology · 2025Review
- The impact of blood flow restriction training on tendon adaptation and tendon rehabilitation - a scoping review.BMC musculoskeletal disorders · 2025Article
- Effects of exercise therapy with blood flow restriction on shoulder strength: protocol for a systematic review and meta-analysis.BMJ open · 2025Article
- Article
- Effect of blood flow restriction training in early postoperative rehabilitation after ACL reconstruction: a randomised controlled trial.Frontiers in sports and active living · 2025Article
- Effects of Blood Flow Restriction Training on Strength and Functionality in People With Knee Arthropathies: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.Translational sports medicine · 2025Review
- Effects of Low-Load Blood Flow Restriction Training on Muscle Volume After Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis.Orthopaedic journal of sports medicine · 2024Review
- Polydatin protects against articular cartilage degeneration by regulating autophagy mediated by the AMPK/mTOR signaling pathway.Histology and histopathology · 2024Article
- Study on the effect of blood flow restriction training combined with IASTAM on ankle strength and function intervention in athletes with chronic ankle instability in sport dance events.BMC sports science, medicine & rehabilitation · 2024Article
- Short-Term Impact of Low-Intensity Exercise with Blood Flow Restriction on Mild Knee Osteoarthritis in Older Adults: A Pilot Study.Healthcare (Basel, Switzerland) · 2024Article
- Quadriceps vascular occlusion does not alter muscle action or balance: A cross-sectional study.The South African journal of physiotherapy · 2024Article
- The Impact of Blood Flow Restriction Training on Tibial Bone Stress Injury Rehabilitation: An Exploratory Case Series.International journal of sports physical therapy · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients undergoing anterior cruciate ligament (ACL) reconstruction and patients suffering from knee osteoarthritis (KOA) have been shown to have quadriceps muscle weakness and/or atrophy in common. The physiological mechanisms of blood flow restriction (BFR) training could facilitate muscle hypertrophy. The purpose of this systematic review is to investigate the effects of BFR training on quadriceps cross-sectional area (CSA), pain perception, function and quality of life on these patients compared to a non-BFR training. A literature research was performed using Web of Science, PEDro, Scopus, MEDLINE, Dialnet, CINAHL and The Cochrane Library databases. The main inclusion criteria were that papers were English or Spanish language reports of randomized controlled trials involving patients with ACL reconstruction or suffering from KOA. The initial research identified 159 publications from all databases; 10 articles were finally included. The search was conducted from April to June 2020. Four of these studies found a significant improvement in strength. A significant increase in CSA was found in two studies. Pain significantly improved in four studies and only one study showed a significant improvement in functionality/quality of life. Low-load training with BFR may be an effective option treatment for increasing quadriceps strength and CSA, but more research is needed.
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Registered trials
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