ArticleDiagnostics (Basel, Switzerland)2020
Diagnostic Value of CEUS Prompting Liver Biopsy: Histopathological Correlation of Hepatic Lesions with Ambiguous Imaging Characteristics.
Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Contrast-enhanced ultrasound for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease.The Cochrane database of systematic reviews · 2022Pooled it
- Impact of structured reporting on interpretability of PSMA PET/CT in prostate cancer staging-towards standardised clinical implementation.European radiology experimental · 2026Article
- Microvascular Imaging of Hepatic Hemangiomas.Diagnostics (Basel, Switzerland) · 2025Article
- Improving diagnostic accuracy in cirrhotic patients: a comprehensive multicenter analysis of contrast-enhanced ultrasound-guided biopsy in a large cohort of 2056 patients.La Radiologia medica · 2025Article
- Ultrasound—New Techniques Are Extending the Applications.Deutsches Arzteblatt international · 2023Article
- Modified contrast-enhanced ultrasonography with the new high-resolution examination technique of high frame rate contrast-enhanced ultrasound (HiFR-CEUS) for characterization of liver lesions: First results.Clinical hemorheology and microcirculation · 2023Article
- Abdominal Ultrasound and Treatment of Hepatocellular Carcinoma.Diagnostics (Basel, Switzerland) · 2021Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundContrast-enhanced ultrasound (CEUS) allows for dynamic analysis of vascularization patterns of unclear hepatic lesions. Our study aimed to evaluate the diagnostic performance of CEUS for further characterizing suspicious liver lesions by comparing findings from CEUS examinations with corresponding histopathology.
methodsBetween 2005 and 2016, 160 patients with unclear liver lesions underwent CEUS followed by liver biopsy. All examinations were performed by an experienced consultant radiologist (EFSUMB Level 3) and included native B-mode ultrasound, Color Doppler, and CEUS. A second-generation blood pool contrast agent was applied for CEUS.
resultsCEUS was successfully performed in all patients without occurrence of any adverse side effects. CEUS showed a sensitivity of 94.5%, a specificity of 70.6%, a true positive rate of 87.3%, and a true negative rate of 85.7% compared to histopathological results as the reference standard.
conclusionsCEUS represents a safe imaging modality with a high diagnostic accuracy in assessing both-benign and malignant-liver lesions compared to corresponding histopathological results.
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