Evidence map›Paper›PMID 33375490›Full record

ArticleJournal of fungi (Basel, Switzerland)2020

A Screen for Small Molecules to Target

Matthew B Lohse, Craig L Ennis, Nairi Hartooni, Alexander D Johnson, Clarissa J Nobile

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Pyrrolidine-Based Antifungal Agents AgainstPharmaceuticals (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Review
  4. Fungal Biofilms 2020.Journal of fungi (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Matthew B LohseDepartment of Microbiology and Immunology, University of California-San Francisco, San Francisco, CA 94158, USA.
Craig L EnnisQuantitative and Systems Biology Graduate Program, University of California-Merced, Merced, CA 95343, USA.ORCID 0000-0001-6497-0397
Nairi HartooniDepartment of Microbiology and Immunology, University of California-San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0003-1740-6253
Alexander D JohnsonDepartment of Microbiology and Immunology, University of California-San Francisco, San Francisco, CA 94158, USA.
Clarissa J NobileDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California-Merced, Merced, CA 95343, USA.ORCID 0000-0003-0799-6499
University of California, San Francisco · USUniversity of California, Merced · US

Funding

The transcriptional circuitry controlling biofilm development in Candida albicansR01AI083311 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, ALEXANDER D · 2011 to 2020
$4.3M
Genetic regulation of inter- and intra-species microbial community formationR35GM124594 · NIGMS · UNIVERSITY OF CALIFORNIA, MERCED · PI NOBILE, CLARISSA JANE · 2017 to 2021
$2.0M
Development of Novel Protease Activity-Based Diagnostics for the Rapid Identification of Candida InfectionsR43AI131710 · NIAID · BIOSYNESIS, INC. · PI LOHSE, MATTHEW B. · 2017 to 2018
$596k
Development of Therapeutics to Treat Candida albicans Biofilm InfectionsR41AI112038 · NIAID · BIOSYNESIS, INC. · PI NOBILE, CLARISSA JANE · 2015 to 2015
$225k
Genetic regulation of antifungal drug resistance in Candida albicansF31DE028488 · NIDCR · UNIVERSITY OF CALIFORNIA, MERCED · PI ENNIS, CRAIG LEWIS · 2019 to 2021
$101k
NIAID NIH HHS R01 AI083311NIAID NIH HHS R41 AI112038NIAID NIH HHS R43 AI131710NIDCR NIH HHS F31 DE028488NIGMS NIH HHS R35 GM124594
6 · The paper itself

Abstract

The human fungal pathogen

Indexed as

antimicrobial resistancebiofilm disruptionbiofilm inhibitionbiofilmsCandida albicansChembridge Small Molecule Diversity libraryhigh-throughput screenstherapeutics

Identifiers

PMID33375490
PMCPMC7824004
OpenAlexW3116450272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.