Evidence map›Paper›PMID 33375315›Full record

ArticleBrain sciences2020

Evidence of fNIRS-Based Prefrontal Cortex Hypoactivity in Obesity and Binge-Eating Disorder.

Sarah A Rösch, Ricarda Schmidt, Michael Lührs, Ann-Christine Ehlis, Swen Hesse, Anja Hilbert

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 41 citations in OpenAlex.

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  5. Prefrontal oxygenation during verbal fluency in severe obesity.Journal of neural transmission (Vienna, Austria : 1996) · 2026
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  8. Prefrontal Cortex Recruitment to Food Stimuli Differs in Overweight/Obesity and Binge Eating Disorder.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
  9. ExoTMS transcranial magnetic stimulation for the reduction of binge eating symptoms.PCN reports : psychiatry and clinical neurosciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Sarah A RöschIntegrated Research and Treatment Center Adiposity Diseases, Behavioural Medicine Research Unit, Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, Semmelweisstrasse 10, 04103 Leipzig, Germany.ORCID 0000-0001-5439-8147
Ricarda SchmidtIntegrated Research and Treatment Center Adiposity Diseases, Behavioural Medicine Research Unit, Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, Semmelweisstrasse 10, 04103 Leipzig, Germany.ORCID 0000-0001-7794-2897
Michael LührsBrain Innovation B.V., Oxfordlaan 55, 6229 EV Maastricht, The Netherlands.
Ann-Christine EhlisDepartment of Psychiatry and Psychotherapy, University of Tübingen, Calwerstrasse 14, 72076 Tübingen, Germany.
Swen HesseDepartment of Nuclear Medicine, University of Leipzig Medical Center, Liebigstrasse 18, 04103 Leipzig, Germany.
Anja HilbertIntegrated Research and Treatment Center Adiposity Diseases, Behavioural Medicine Research Unit, Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, Semmelweisstrasse 10, 04103 Leipzig, Germany.
IFB Adiposity Diseases · DELeipzig University · DEMaastricht University · NLMax Planck Institute for Human Cognitive and Brain Sciences · DEUniversity of Tübingen · DE

Funding

Cusanuswerk PhD scholarshipGerman Federal Ministry of Education and Research 01EO1501
6 · The paper itself

Abstract

Obesity (OB) and associated binge-eating disorder (BED) show increased impulsivity and emotional dysregulation. Albeit well-established in neuropsychiatric research, functional near-infrared spectroscopy (fNIRS) has rarely been used to study OB and BED. Here, we investigated fNIRS-based food-specific brain signalling, its association with impulsivity and emotional dysregulation, and the temporal variability in individuals with OB with and without BED compared to an age- and sex-stratified normal weight (NW) group. Prefrontal cortex (PFC) responses were recorded in individuals with OB (

Indexed as

binge-eating disorderemotional dysregulationfNIRSimpulsivityobesityprefrontal cortex

Identifiers

PMID33375315
PMCPMC7823505
OpenAlexW3115280171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.