Evidence map›Paper›PMID 33375294›Full record

ArticlePharmaceutics2020

Lactoferrin-Anchored Tannylated Mesoporous Silica Nanomaterials for Enhanced Osteo-Differentiation Ability.

Sung Hyun Noh, Han-Saem Jo, Somang Choi, Hee Gyeong Song, Hak-Jun Kim, Keung Nyun Kim, Sung Eun Kim, Kyeongsoon Park

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Sung Hyun NohDepartment of Neurosurgery, National Health Insurance Service Ilsan Hospital, #100, Ilsan-ro, Ilsan-donggu, Gyeonggi-do, Goyang-si 10444, Korea.
Han-Saem JoDepartment of Systems Biotechnology, Chung-Ang University, Gyeonggi-do, Anseong-si 17546, Korea.
Somang ChoiDepartment of Orthopedic Surgery and Rare Diseases Institute, Korea University Guro Hospital, #148, Gurodong-ro, Guro-gu, Seoul 08308, Korea.
Hee Gyeong SongDepartment of Systems Biotechnology, Chung-Ang University, Gyeonggi-do, Anseong-si 17546, Korea.
Hak-Jun KimDepartment of Orthopedic Surgery and Rare Diseases Institute, Korea University Guro Hospital, #148, Gurodong-ro, Guro-gu, Seoul 08308, Korea.
Keung Nyun KimDepartment of Neurosurgery, Spine and Spinal Cord Institute, Severance Hospital, Yonsei University, College of Medicine, #50, Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea.
Sung Eun KimDepartment of Orthopedic Surgery and Rare Diseases Institute, Korea University Guro Hospital, #148, Gurodong-ro, Guro-gu, Seoul 08308, Korea.
Kyeongsoon ParkDepartment of Systems Biotechnology, Chung-Ang University, Gyeonggi-do, Anseong-si 17546, Korea.ORCID 0000-0003-3625-4128
Chung-Ang University · KRKorea University Medical Center · KRNational Health Insurance Service Ilsan Hospital · KRYonsei University · KR

Funding

National Health Insurance Service Ilsan Hospital NHIMC2020CR001
6 · The paper itself

Abstract

In the present study, we created lactoferrin-anchored mesoporous silica nanomaterials with absorbed tannic acid (LF/TA-MSNs) and evaluated the effect of these LF/TA-MSNs on the in vitro osteo-differentiation ability of adipose-derived stem cells (ADSCs) by testing alkaline phosphatase (ALP) level, calcium accumulation, and expression of osteo-differentiation-specific genes, including osteocalcin (

Indexed as

adipose-derived stem cellslactoferrinmesoporous silica nanomaterialsosteo-differentiation ability

Identifiers

PMID33375294
PMCPMC7823981
OpenAlexW3118174103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.