ArticleSensors (Basel, Switzerland)2020
A New Paper-Based Microfluidic Device for Improved Detection of Nitrate in Water.
Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- From pen to paper-based screening: an early-stage colorimetric µPAD with desktop-app readout for lead and nitrite.RSC advances · 2026Article
- Paper-Based Microfluidic Devices: A Powerful Strategy for Rapid Detection.Micromachines · 2025Review
- Smart Paper-Based Nanosensor for Simultaneous Environmental eMonitoring of Nitrate and Nitrite.ACS measurement science au · 2025Article
- Portable Multispectral Imaging System for Sodium Nitrite Detection via Griess Reaction on Cellulose Fiber Sample Pads.Sensors (Basel, Switzerland) · 2025Article
- Sustainable Sensing with Paper Microfluidics: Applications in Health, Environment, and Food Safety.Biosensors · 2024Review
- A multi-line platinum nanozyme-based lateral flow device for the colorimetric evaluation of total antioxidant capacity in different matrices.Nanoscale advances · 2023Article
- Near-Field Communication Tag for Colorimetric Glutathione Determination with a Paper-Based Microfluidic Device.Biosensors · 2023Article
- Maximizing flow rate in single paper layer, rapid flow microfluidic paper-based analytical devices.Microfluidics and nanofluidics · 2023Article
- Porous Cellulose Substrate Study to Improve the Performance of Diffusion-Based Ionic Strength Sensors.Membranes · 2022Article
- A Lateral Flow Device for Point-of-Care Detection of Doxorubicin.Biosensors · 2022Article
- Application of Microfluidic Chips in the Detection of Airborne Microorganisms.Micromachines · 2022Review
- A Parametric Study on a Paper-Based Bi-Material Cantilever Valve.Micromachines · 2022Article
- Portable Colorimetric Device with Commercial Microplates for Quantitative Detection of Urine Biomarkers: Design, Development, and Clinical Evaluation.Biosensors · 2022Article
- Droplet Microfluidic Device for Chemoenzymatic Sensing.Micromachines · 2022Article
- Improvement ofSensors (Basel, Switzerland) · 2022Article
- A Colorimetric Dip Strip Assay for Detection of Low Concentrations of Phosphate in Seawater.Sensors (Basel, Switzerland) · 2021Article
- An Improved Algorithm for Measuring Nitrate Concentrations in Seawater Based on Deep-Ultraviolet Spectrophotometry: A Case Study of the Aoshan Bay Seawater and Western Pacific Seawater.Sensors (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
In this paper, we report a simple and inexpensive paper-based microfluidic device for detecting nitrate in water. This device incorporates two recent developments in paper-based technology suitable for nitrate detection and has an optimized microfluidic design. The first technical advancement employed is an innovative fibrous composite material made up of cotton fibers and zinc microparticles that can be incorporated in paper-based devices and results in better nitrate reduction. The second is a detection zone with an immobilized reagent that allows the passage of a larger sample volume. Different acids were tested-citric and phosphoric acids gave better results than hydrochloric acid since this acid evaporates completely without leaving any residue behind on paper. Different microfluidic designs that utilize various fluid control technologies were investigated and a design with a folding detection zone was chosen and optimized to improve the uniformity of the signal produced. The optimized design allowed the device to achieve a limit of detection and quantification of 0.53 ppm and 1.18 ppm, respectively, for nitrate in water. This accounted for more than a 40% improvement on what has been previously realized for the detection of nitrate in water using paper-based technology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.