Evidence map›Paper›PMID 33375202›Full record

ReviewDiagnostics (Basel, Switzerland)2020

The Role of Gut, Vaginal, and Urinary Microbiome in Urinary Tract Infections: From Bench to Bedside.

Tomislav Meštrović, Mario Matijašić, Mihaela Perić, Hana Čipčić Paljetak, Anja Barešić, Donatella Verbanac

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05335213 (Urinary Tract Infections in Cirrhosis), which is not on this map. Cited by 85 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 1 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05335213 unknown statusnot on this mapstarted 2022, after this paper: background citation

Urinary Tract Infections in Cirrhosis

Typeobservational_patient_registrySponsorGomel State Medical UniversityRan2022 to 2024Enrolled35ConditionsLiver Cirrhosis, Urinary Tract InfectionsArms16S rRNA gene sequencing
3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Efficacy ofNutrients · 2024
    Trial
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Contrasting pH optima of β-lactamases CTX-M and CMY influenceApplied and environmental microbiology · 2026
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Molecular characterization of ESBL-producingFrontiers in cellular and infection microbiology · 2026
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tomislav MeštrovićUniversity Centre Varaždin, University North, 42 000 Varaždin, Croatia.
Mario MatijašićCenter for Translational and Clinical Research, University of Zagreb School of Medicine, 10 000 Zagreb, Croatia.ORCID 0000-0001-9209-4611
Mihaela PerićCenter for Translational and Clinical Research, University of Zagreb School of Medicine, 10 000 Zagreb, Croatia.
Hana Čipčić PaljetakCenter for Translational and Clinical Research, University of Zagreb School of Medicine, 10 000 Zagreb, Croatia.
Anja BarešićDivision of Electronics, Ruđer Bošković Institute, 10 000 Zagreb, Croatia.ORCID 0000-0003-1303-3031
Donatella VerbanacFaculty of Pharmacy and Biochemistry, University of Zagreb, 10 000 Zagreb, Croatia.
University of Zagreb · HRRuđer Bošković Institute · HRUniversity North · HR

Funding

Hrvatska Zaklada za Znanost IP-11-2013-5467Scientific Center of Excellence for Reproductive and Regenerative Medicine GA KK.01.1.1.01.0008
6 · The paper itself

Abstract

The current paradigm of urinary tract infection (UTI) pathogenesis takes into account the contamination of the periurethral space by specific uropathogens residing in the gut, which is followed by urethral colonization and pathogen ascension to the urinary bladder. Consequently, studying the relationship between gut microbiota and the subsequent development of bacteriuria and UTI represents an important field of research. However, the well-established diagnostic and therapeutic paradigm for urinary tract infections (UTIs) has come into question with the discovery of a multifaceted, symbiotic microbiome in the healthy urogenital tract. More specifically, emerging data suggest that vaginal dysbiosis may result in

Indexed as

bacteriuriadysbiosisgut microbiomemicrobiomemicrobiotaurinary tracturinary tract infectionurobiomeUTIvaginal microbiome

Identifiers

PMID33375202
PMCPMC7822161
OpenAlexW3114792568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.