Evidence map›Paper›PMID 33375170›Full record

ArticleInternational journal of molecular sciences2020

Restoration of Sarcoplasmic Reticulum Ca

Rizwan Qaisar, Gavin Pharaoh, Shylesh Bhaskaran, Hongyang Xu, Rojina Ranjit, Jan Bian, Bumsoo Ahn, Constantin Georgescu, Jonathan D Wren, Holly Van Remmen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Review
  3. iPLAScience advances · 2026
    Article
  4. Review
  5. The two faces of mitochondrial CaJournal of physiology and biochemistry · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Reactive oxygen species in the pathogenesis of sarcopenia.Free radical biology & medicine · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Rizwan QaisarAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
Gavin PharaohAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
Shylesh BhaskaranAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
Hongyang XuAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
Rojina RanjitAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
Jan BianAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
Bumsoo AhnAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
Constantin GeorgescuDivision of Genomics and Data Sciences, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
Jonathan D WrenDivision of Genomics and Data Sciences, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
Holly Van RemmenAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
Oklahoma Medical Research Foundation · USUniversity of Sharjah · AE

Funding

AFAR Irene Diamond Postdoctoral awardVA merit grant I01BX004453-01A1
6 · The paper itself

Abstract

Sarcopenia has a significant negative impact on healthspan in the elderly and effective pharmacologic interventions remain elusive. We have previously demonstrated that sarcopenia is associated with reduced activity of the sarcoplasmic reticulum Ca

Indexed as

Age FactorsAminoquinolinesAnimalsBenzamidesEnzyme ActivationInjections, IntraperitonealMaleMAP Kinase Signaling SystemMice, Inbred C57BLMitochondria, MuscleMuscle, SkeletalMuscle WeaknessMuscular AtrophyPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaReactive Oxygen SpeciesSarcoplasmic Reticulum Calcium-Transporting ATPasesAminoquinolinesBenzamidesCDN1163Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPpargc1a protein, mouseReactive Oxygen SpeciesSarcoplasmic Reticulum Calcium-Transporting ATPasesUncoupling Protein 1sarcopeniasarcoplasmic reticulum calcium-transporting ATPaseskeletal muscle

Identifiers

PMID33375170
PMCPMC7792969
OpenAlexW3113559345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.