Evidence map›Paper›PMID 33375166›Full record

ArticleCells2020

Modeling CNS Involvement in Pompe Disease Using Neural Stem Cells Generated from Patient-Derived Induced Pluripotent Stem Cells.

Yu-Shan Cheng, Shu Yang, Junjie Hong, Rong Li, Jeanette Beers, Jizhong Zou, Wenwei Huang, Wei Zheng

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. IGF2-associated tumor cells and APOE-positive macrophages define an imatinib resistance-associated niche in gastrointestinal stromal tumors.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  4. Review
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  7. Review
  8. Article
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  11. Article
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  13. Article
  14. Neurological glycogen storage diseases and emerging therapeutics.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Review
  15. Review
  16. Review
  17. Review
  18. [Research progress of nervous system damage in Pompe disease].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Review
  19. Article
  20. Induced pluripotent stem cell for modeling Pompe disease.Frontiers in cardiovascular medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yu-Shan ChengNational Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA.
Shu YangNational Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0001-8909-1962
Junjie HongNational Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA.
Rong LiNational Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA.
Jeanette BeersiPSC Core Facility, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Jizhong ZouiPSC Core Facility, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Wenwei HuangNational Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA.
Wei ZhengNational Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0003-1034-0757
National Institutes of Health · US

Funding

Drug Repurposing Screening for Rare and Neglected DiseasesZIATR000018 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI ZHENG, WEI · 2015 to 2025
$24.6M
6 · The paper itself

Abstract

Pompe disease is a lysosomal storage disorder caused by autosomal recessive mutations in the

Indexed as

Glycogen Storage Disease Type II2-Hydroxypropyl-beta-cyclodextrinalpha-GlucosidasesCell LineFibroblastsgamma-TocopherolHumansInduced Pluripotent Stem CellsNeural Stem Cells2-Hydroxypropyl-beta-cyclodextrinalpha-GlucosidasesGAA protein, humangamma-Tocopherolcell-based disease modelinduced pluripotent stem cellslysosomal storage diseaseneural stem cellsPompe disease

Identifiers

PMID33375166
PMCPMC7822217
OpenAlexW3114766316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.