Evidence map›Paper›PMID 33375120›Full record

ArticleInternational journal of molecular sciences2020

Novel Allergen Discovery through Comprehensive De Novo Transcriptomic Analyses of Five Shrimp Species.

Shaymaviswanathan Karnaneedi, Roger Huerlimann, Elecia B Johnston, Roni Nugraha, Thimo Ruethers, Aya C Taki, Sandip D Kamath, Nicholas M Wade, Dean R Jerry, Andreas L Lopata

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. The allergenic potential of enolases: physiological and pathophysiological insights.Current opinion in allergy and clinical immunology · 2025
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Impact of Enolase in Allergic Disease.Current allergy and asthma reports · 2024
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Shrimp-allergic patients in a multi-food oral immunotherapy trial.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Shaymaviswanathan KarnaneediMolecular Allergy Research Laboratory, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD 4811, Australia.ORCID 0000-0003-2384-2625
Roger HuerlimannARC Research Hub for Advanced Prawn Breeding, Townsville, QLD 4811, Australia.
Elecia B JohnstonMolecular Allergy Research Laboratory, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD 4811, Australia.ORCID 0000-0003-0927-6524
Roni NugrahaMolecular Allergy Research Laboratory, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD 4811, Australia.ORCID 0000-0001-5935-5867
Thimo RuethersMolecular Allergy Research Laboratory, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD 4811, Australia.ORCID 0000-0002-0856-3452
Aya C TakiMolecular Allergy Research Laboratory, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD 4811, Australia.ORCID 0000-0003-3489-4367
Sandip D KamathMolecular Allergy Research Laboratory, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD 4811, Australia.
Nicholas M WadeARC Research Hub for Advanced Prawn Breeding, Townsville, QLD 4811, Australia.
Dean R JerryARC Research Hub for Advanced Prawn Breeding, Townsville, QLD 4811, Australia.ORCID 0000-0003-3735-1798
Andreas L LopataMolecular Allergy Research Laboratory, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD 4811, Australia.
Royal Children's Hospital · AUAustralian Institute of Tropical Health and Medicine · AUCommonwealth Scientific and Industrial Research Organisation · AUIPB University · IDJames Cook University Singapore · SG

Funding

Australian Research Council IH130200013National Health and Medical Research Council APP1086656
6 · The paper itself

Abstract

Shellfish allergy affects 2% of the world's population and persists for life in most patients. The diagnosis of shellfish allergy, in particular shrimp, is challenging due to the similarity of allergenic proteins from other invertebrates. Despite the clinical importance of immunological cross-reactivity among shellfish species and between allergenic invertebrates such as dust mites, the underlying molecular basis is not well understood. Here we mine the complete transcriptome of five frequently consumed shrimp species to identify and compare allergens with all known allergen sources. The transcriptomes were assembled de novo, using Trinity, from raw RNA-Seq data of the whiteleg shrimp (

Indexed as

AllergensAnimalsArthropod ProteinsCross ReactionsEvolution, MolecularFood HypersensitivityGene Expression ProfilingHumansPenaeidaePhylogenySeafoodSpecies SpecificityTranscriptomeTropomyosinAllergensArthropod ProteinsTropomyosinallergenallergyprawnRNA-Seqtropomyosin

Identifiers

PMID33375120
PMCPMC7792927
OpenAlexW3116132919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.