Evidence map›Paper›PMID 33375068›Full record

ArticleEntropy (Basel, Switzerland)2020

Computing Integrated Information (

Juan D Gomez, William G P Mayner, Maggie Beheler-Amass, Giulio Tononi, Larissa Albantakis

Abstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Mechanism Integrated Information.Entropy (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juan D GomezDepartment of Psychiatry, Wisconsin Institute for Sleep and Consciousness, University of Wisconsin-Madison, Madison, WI 53719, USA.
William G P MaynerDepartment of Psychiatry, Wisconsin Institute for Sleep and Consciousness, University of Wisconsin-Madison, Madison, WI 53719, USA.ORCID 0000-0002-9737-6260
Maggie Beheler-AmassDepartment of Psychiatry, Wisconsin Institute for Sleep and Consciousness, University of Wisconsin-Madison, Madison, WI 53719, USA.
Giulio TononiDepartment of Psychiatry, Wisconsin Institute for Sleep and Consciousness, University of Wisconsin-Madison, Madison, WI 53719, USA.
Larissa AlbantakisDepartment of Psychiatry, Wisconsin Institute for Sleep and Consciousness, University of Wisconsin-Madison, Madison, WI 53719, USA.ORCID 0000-0003-1000-9917

Funding

Templeton World Charity Foundation TWCF0196Tiny Blue Dot Foundation UW 133AAG3451
6 · The paper itself

Abstract

Integrated information theory (IIT) provides a mathematical framework to characterize the cause-effect structure of a physical system and its amount of integrated information (Φ). An accompanying Python software package ("PyPhi") was recently introduced to implement this framework for the causal analysis of discrete dynamical systems of binary elements. Here, we present an update to PyPhi that extends its applicability to systems constituted of discrete, but multi-valued elements. This allows us to analyze and compare general causal properties of random networks made up of binary, ternary, quaternary, and mixed nodes. Moreover, we apply the developed tools for causal analysis to a simple non-binary regulatory network model (p53-Mdm2) and discuss commonly used binarization methods in light of their capacity to preserve the causal structure of the original system with multi-valued elements.

Indexed as

binarizationcausationcoarse grainingregulatory networks

Identifiers

PMID33375068
PMCPMC7822016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.