Evidence map›Paper›PMID 33374915›Full record

ArticleInternational journal of molecular sciences2020

Regulator of G Protein Signalling 4 (RGS4) as a Novel Target for the Treatment of Sensorineural Hearing Loss.

Christine Fok, Milan Bogosanovic, Madhavi Pandya, Ravindra Telang, Peter R Thorne, Srdjan M Vlajkovic

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Purinergic Signalling in the Cochlea.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Christine FokDepartment of Physiology and The Eisdell Moore Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Milan BogosanovicDepartment of Physiology and The Eisdell Moore Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Madhavi PandyaDepartment of Physiology and The Eisdell Moore Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Ravindra TelangDepartment of Physiology and The Eisdell Moore Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Peter R ThorneDepartment of Physiology and The Eisdell Moore Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Srdjan M VlajkovicDepartment of Physiology and The Eisdell Moore Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.ORCID 0000-0001-8548-6844
University of Auckland · NZ

Funding

Auckland Medical Research Foundation 1115013
6 · The paper itself

Abstract

We and others have previously identified signalling pathways associated with the adenosine A

Indexed as

AnimalsAuditory ThresholdCochleaEvoked Potentials, Auditory, Brain StemHair Cells, AuditoryHearing Loss, Noise-InducedHearing Loss, SensorineuralMaleMicrofilament ProteinsNerve Tissue ProteinsNeurabinsRats, WistarReceptor, Adenosine A1RGS ProteinsSignal TransductionSulfonamidesmethyl N-((4-chlorophenyl)sulfonyl)-4-nitrobenzenesulfinimidoateMicrofilament ProteinsNerve Tissue ProteinsNeurabinsReceptor, Adenosine A1RGS4 proteinRGS ProteinsSulfonamidesadenosine A1 receptorCCG-4986cochlear rescueintratympanic drug deliverynoise-induced cochlear injuryotoprotectionregulator of G protein signalling 4sensorineural hearing loss

Identifiers

PMID33374915
PMCPMC7792627
OpenAlexW3115311677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.