Evidence map›Paper›PMID 33374863›Full record

ArticleMarine drugs2020

The Remarkable Antioxidant and Anti-Inflammatory Potential of the Extracts of the Brown Alga

Gina De La Fuente, Marco Fontana, Valentina Asnaghi, Mariachiara Chiantore, Serena Mirata, Annalisa Salis, Gianluca Damonte, Sonia Scarfì

Abstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Comparative metabolic study of the chloroform fraction of threeJournal of enzyme inhibition and medicinal chemistry · 2024
    Article
  4. Article
  5. The Ocean's Pharmacy: Health Discoveries in Marine Algae.Molecules (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Keep It Simple: Improving the Ex Situ Culture ofPlants (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Volatile Organic Compound Profiles ofMolecules (Basel, Switzerland) · 2022
    Article
  13. Molecules (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Marine drugs · 2021
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gina De La FuenteDepartment of Earth, Environment and Life Sciences (DISTAV), University of Genova, Via Pastore 3, 16132 Genova, Italy.ORCID 0000-0003-1222-9091
Marco FontanaDepartment of Earth, Environment and Life Sciences (DISTAV), University of Genova, Via Pastore 3, 16132 Genova, Italy.
Valentina AsnaghiDepartment of Earth, Environment and Life Sciences (DISTAV), University of Genova, Via Pastore 3, 16132 Genova, Italy.
Mariachiara ChiantoreDepartment of Earth, Environment and Life Sciences (DISTAV), University of Genova, Via Pastore 3, 16132 Genova, Italy.
Serena MirataDepartment of Earth, Environment and Life Sciences (DISTAV), University of Genova, Via Pastore 3, 16132 Genova, Italy.
Annalisa SalisCentre of Excellence for Biomedical Research (CEBR), University of Genova, Viale Benedetto XV 9, 16132 Genova, Italy.ORCID 0000-0002-3082-2908
Gianluca DamonteCentre of Excellence for Biomedical Research (CEBR), University of Genova, Viale Benedetto XV 9, 16132 Genova, Italy.ORCID 0000-0001-8769-2051
Sonia ScarfìDepartment of Earth, Environment and Life Sciences (DISTAV), University of Genova, Via Pastore 3, 16132 Genova, Italy.ORCID 0000-0002-7079-6919

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation and oxidative stress are part of the complex biological responses of body tissues to harmful stimuli. In recent years, due to the increased understanding that oxidative stress is implicated in several diseases, pharmaceutical industries have invested in the research and development of new antioxidant compounds, especially from marine environment sources. Marine seaweeds have shown the presence of many bioactive secondary metabolites, with great potentialities from both the nutraceutical and the biomedical point of view. In this study, 50%-ethanolic and DMSO extracts from the species

Indexed as

AnimalsAnti-Inflammatory AgentsAntioxidantsCyclooxygenase 2CytokinesFibroblastsHydrogen PeroxideInflammation MediatorsLipopolysaccharidesMacrophagesMiceNitric OxideNitric Oxide Synthase Type IIOxidative StressPhaeophyceaeRAW 264.7 CellsAnti-Inflammatory AgentsAntioxidantsCyclooxygenase 2CytokinesHydrogen PeroxideInflammation MediatorsLipopolysaccharidesNitric OxideNitric Oxide Synthase Type IINos2 protein, mousePtgs2 protein, mouseReactive Oxygen Speciesbiological effectsbrown algaeFucalesgene expression

Identifiers

PMID33374863
PMCPMC7823636

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.