Evidence map›Paper›PMID 33374769›Full record

ReviewMolecules (Basel, Switzerland)2020

Overview of Inositol and Inositol Phosphates on Chemoprevention of Colitis-Induced Carcinogenesis.

Samuel E Weinberg, Le Yu Sun, Allison L Yang, Jie Liao, Guang Yu Yang

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Inositol in Disease and Development: Roles of Catabolism viaInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. Review
  10. Bioactivity of Inositol Phosphates.Molecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Samuel E WeinbergDepartment of Pathology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA.ORCID 0000-0002-9532-7051
Le Yu SunDepartment of Pathology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA.
Allison L YangDivision of Gastroenterology and Hepatology, Weill Cornell Medicine, 1293 York Avenue, New York, NY 10065, USA.
Jie LiaoDepartment of Pathology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA.
Guang Yu YangDepartment of Pathology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA.
Northwestern University · USCornell University · US

Funding

Omega-3 derived epoxy fatty acids and sEH in pancreatitis-induced carcinogenesisR01DK107767 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI YANG, GUANG-YU · 2016 to 2019
$1.9M
Inhibition of pancreatic carcinogenesis via targeting c-Raf and sEHR01CA172431 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI YANG, GUANG-YU · 2013 to 2017
$1.6M
Aldo-keto reductase family 1 member B10 AKR1B10 in pancreatic carcinogenesisR01CA164041 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI YANG, GUANG-YU · 2012 to 2016
$1.6M
Soluble epoxide hydrolase as a novel target of colitis-induced carcinogenesisR01CA137467 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI YANG, GUANG-YU · 2009 to 2012
$1.2M
Ulcerative colitis-associated cancer and its preventionR01CA104741 · NCI · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI YANG, GUANG-YU · 2004 to 2008
$1.2M
NCI NIH HHS R01 CA104741NCI NIH HHS R01 CA137467NCI NIH HHS R01 CA164041NCI NIH HHS R01 CA172431NIDDK NIH HHS DK10776NIDDK NIH HHS R01 DK107767NIH HHS CA164041NIH HHS CA172431
6 · The paper itself

Abstract

Chronic inflammation is one of the most common and well-recognized risk factors for human cancer, including colon cancer. Inflammatory bowel disease (IBD) is defined as a longstanding idiopathic chronic active inflammatory process in the colon, including ulcerative colitis and Crohn's disease. Importantly, patients with IBD have a significantly increased risk for the development of colorectal carcinoma. Dietary inositol and its phosphates, as well as phospholipid derivatives, are well known to benefit human health in diverse pathologies including cancer prevention. Inositol phosphates including InsP

Indexed as

AnimalsColitisColonic NeoplasmsHumansInositolInositol PhosphatesInositolInositol Phosphatescarcinogenesischemopreventioncolitisinositolinositol phosphates

Identifiers

PMID33374769
PMCPMC7796135
OpenAlexW3115955494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.