Evidence map›Paper›PMID 33374717›Full record

ArticleBiology2020

Drug Repurposing Approach against Novel Coronavirus Disease (COVID-19) through Virtual Screening Targeting SARS-CoV-2 Main Protease.

Kamrul Hasan Chowdhury, Md Riad Chowdhury, Shafi Mahmud, Abu Montakim Tareq, Nujhat Binte Hanif, Naureen Banu, A S M Ali Reza, Talha Bin Emran, Jesus Simal-Gandara

Open access · goldAbstract read
In one paragraph

Article in Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 91 citations in OpenAlex.

  1. Machine learning-guided rational engineering of ACE2-derived peptides for broad-spectrum neutralization of SARS-CoV-2 variants.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
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  11. Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Kamrul Hasan ChowdhuryDepartment of Pharmacy, International Islamic University Chittagong, Chittagong 4318, Bangladesh.
Md Riad ChowdhuryDepartment of Pharmacy, International Islamic University Chittagong, Chittagong 4318, Bangladesh.
Shafi MahmudMicrobiology Laboratory, Bioinformatics Division, Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi 6205, Bangladesh.
Abu Montakim TareqDepartment of Pharmacy, International Islamic University Chittagong, Chittagong 4318, Bangladesh.ORCID 0000-0003-2704-7610
Nujhat Binte HanifDepartment of Pharmacy, International Islamic University Chittagong, Chittagong 4318, Bangladesh.
Naureen BanuDepartment of Pharmacy, International Islamic University Chittagong, Chittagong 4318, Bangladesh.
A S M Ali RezaDepartment of Pharmacy, International Islamic University Chittagong, Chittagong 4318, Bangladesh.ORCID 0000-0002-1457-0245
Talha Bin EmranDepartment of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.ORCID 0000-0003-3188-2272
Jesus Simal-GandaraNutrition and Bromatology Group, Department of Analytical and Food Chemistry, Faculty of Food Science and Technology, University of Vigo-Ourense Campus, E32004 Ourense, Spain.ORCID 0000-0001-9215-9737
International Islamic University Chittagong · BDBGC Trust University Bangladesh · BDUniversidade de Vigo · ESUniversity of Rajshahi · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel coronavirus disease (COVID-19) was identified from China in December 2019 and spread rapidly through human-to-human transmission, affecting so many people worldwide. Until now, there has been no specific treatment against the disease and repurposing of the drug. Our investigation aimed to screen potential inhibitors against coronavirus for the repurposing of drugs. Our study analyzed sequence comparison among SARS-CoV, SARS-CoV-2, and MERS-CoV to determine the identity matrix using discovery studio. SARS-CoV-2 M

Indexed as

antiviral agentsCOVID-19drug repurposingE-pharmacophore hypothesismolecular dockingmolecular dynamicsvirtual screening

Identifiers

PMID33374717
PMCPMC7822464
OpenAlexW3114991116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.