Evidence map›Paper›PMID 33374698›Full record

ArticleInternational journal of molecular sciences2020

Reduced Gonadotrophin Receptor Expression Is Associated with a More Aggressive Ovarian Cancer Phenotype.

Janelle Cheung, Noor A Lokman, Riya D Abraham, Anne M Macpherson, Eunice Lee, Frank Grutzner, Nicolae Ghinea, Martin K Oehler, Carmela Ricciardelli

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

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  12. CaMKK2 Promotes the Progression of Ovarian Carcinoma through the PI3K/PDK1/Akt Axis.Computational and mathematical methods in medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Janelle CheungAdelaide Medical School, Robinson Research Institute, University of Adelaide, Adelaide, SA 5000, Australia.
Noor A LokmanAdelaide Medical School, Robinson Research Institute, University of Adelaide, Adelaide, SA 5000, Australia.
Riya D AbrahamAdelaide Medical School, Robinson Research Institute, University of Adelaide, Adelaide, SA 5000, Australia.
Anne M MacphersonAdelaide Medical School, Robinson Research Institute, University of Adelaide, Adelaide, SA 5000, Australia.
Eunice LeeSchool of Biological Science, Robinson Research Institute, University of Adelaide, Adelaide, SA 5005, Australia.ORCID 0000-0002-6380-3279
Frank GrutznerSchool of Biological Science, Robinson Research Institute, University of Adelaide, Adelaide, SA 5005, Australia.
Nicolae GhineaCurie Institute, Research Center, Translational Research Department, Tumor Angiogenesis Team, 75005 Paris, France.
Martin K OehlerAdelaide Medical School, Robinson Research Institute, University of Adelaide, Adelaide, SA 5000, Australia.
Carmela RicciardelliAdelaide Medical School, Robinson Research Institute, University of Adelaide, Adelaide, SA 5000, Australia.ORCID 0000-0001-7415-1854
The University of Adelaide · AURoyal Adelaide Hospital · AU

Funding

Cancer Council SA N/AOvarian Cancer Research Foundation N/A
6 · The paper itself

Abstract

Follicle-stimulating hormone (FSH) and luteinising hormone (LH) play important roles in regulating cell growth and proliferation in the ovary. However, few studies have explored the expression of FSH and LH receptors (FSHR and LHCGR) in ovarian cancer, and their functional roles in cancer progression remain inconclusive. This study investigated the potential impact of both mRNA (

Indexed as

Biomarkers, TumorCell Line, TumorFemaleHumansMiddle AgedNeoplasms, Cystic, Mucinous, and SerousOvarian NeoplasmsPhenotypeReceptors, FSHReceptors, LHBiomarkers, TumorFSHR protein, humanLHCGR protein, humanReceptors, FSHReceptors, LHcancer progressionFSHRgonadotropinsLHCGRovarian cancerserous ovarian cancer

Identifiers

PMID33374698
PMCPMC7793521
OpenAlexW3116872725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.