Evidence map›Paper›PMID 33374676›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Effects of a Paediatric Antimicrobial Stewardship Program on Antimicrobial Use and Quality of Prescriptions in Patients with Appendix-Related Intraabdominal Infections.

Sílvia Simó, Eneritz Velasco-Arnaiz, María Ríos-Barnés, María Goretti López-Ramos, Manuel Monsonís, Mireia Urrea-Ayala, Iolanda Jordan, Ricard Casadevall-Llandrich, Daniel Ormazábal-Kirchner, Daniel Cuadras-Pallejà and 5 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sílvia SimóInfectious Diseases and Systemic Inflammatory Response in Paediatrics, Infectious Diseases Unit, Department of Paediatrics, Sant Joan de Déu Hospital Research Foundation, 08950 Barcelona, Spain.ORCID 0000-0003-2115-1695
Eneritz Velasco-ArnaizInfectious Diseases and Systemic Inflammatory Response in Paediatrics, Infectious Diseases Unit, Department of Paediatrics, Sant Joan de Déu Hospital Research Foundation, 08950 Barcelona, Spain.
María Ríos-BarnésInfectious Diseases and Systemic Inflammatory Response in Paediatrics, Infectious Diseases Unit, Department of Paediatrics, Sant Joan de Déu Hospital Research Foundation, 08950 Barcelona, Spain.
María Goretti López-RamosPharmacy Department, Sant Joan de Déu Hospital, 08950 Barcelona, Spain.
Manuel MonsonísClinical Microbiology Department, Sant Joan de Déu Hospital, 08950 Barcelona, Spain.
Mireia Urrea-AyalaPatient Safety Area-Infection Control Unit, Sant Joan de Déu Hospital, 08950 Barcelona, Spain.
Iolanda JordanCentre for Biomedical Network Research on Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0002-2041-4425
Ricard Casadevall-LlandrichManagement Department, Sant Joan de Déu Hospital, 08950 Barcelona, Spain.
Daniel Ormazábal-KirchnerComputing Department, Sant Joan de Déu Hospital, 08950 Barcelona, Spain.
Daniel Cuadras-PallejàStatistics Department, Sant Joan de Déu Research Foundation, 08950 Barcelona, Spain.
Xavier TarradoPaediatric Surgery Department, Sant Joan de Déu Hospital, 08950 Barcelona, Spain.ORCID 0000-0002-8072-7095
Jordi PratPaediatric Surgery Department, Sant Joan de Déu Hospital, 08950 Barcelona, Spain.ORCID 0000-0002-8974-0827
Emília SánchezBlanquerna School of Health Science, Ramon Llull University, 08022 Barcelona, Spain.
Antoni Noguera-JulianInfectious Diseases and Systemic Inflammatory Response in Paediatrics, Infectious Diseases Unit, Department of Paediatrics, Sant Joan de Déu Hospital Research Foundation, 08950 Barcelona, Spain.ORCID 0000-0001-7485-0583
Clàudia FortunyInfectious Diseases and Systemic Inflammatory Response in Paediatrics, Infectious Diseases Unit, Department of Paediatrics, Sant Joan de Déu Hospital Research Foundation, 08950 Barcelona, Spain.

Funding

Departament de Salut, Generalitat de Catalunya SLT008/18/00193Instituto de Salud Carlos III CM18/00054
6 · The paper itself

Abstract

The effectiveness of antimicrobial stewardship programs (ASP) in reducing antimicrobial use (AU) in children has been proved. Many interventions have been described suitable for different institution sizes, priorities, and patients, with surgical wards being one of the areas that may benefit the most. We aimed to describe the results on AU and length of stay (LOS) in a pre-post study during the three years before (2014-2016) and the three years after (2017-2019) implementation of an ASP based on postprescription review with feedback in children and adolescents admitted for appendix-related intraabdominal infections (AR-IAI) in a European Referral Paediatric University Hospital. In the postintervention period, the quality of prescriptions (QP) was also evaluated. Overall, 2021 AR-IAIs admissions were included. Global AU, measured both as days of therapy/100 patient days (DOT/100PD) and length of therapy (LOT), and global LOS remained unchanged in the postintervention period. Phlegmonous appendicitis LOS (

Indexed as

antimicrobial stewardshipappendicitischildrendays of therapyintra-abdominal infectionlength of staypaediatric

Identifiers

PMID33374676
PMCPMC7822420

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.