Evidence map›Paper›PMID 33374672›Full record

ArticleDiagnostics (Basel, Switzerland)2020

In-Series U-Net Network to 3D Tumor Image Reconstruction for Liver Hepatocellular Carcinoma Recognition.

Wen-Fan Chen, Hsin-You Ou, Keng-Hao Liu, Zhi-Yun Li, Chien-Chang Liao, Shao-Yu Wang, Wen Huang, Yu-Fan Cheng, Cheng-Tang Pan

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wen-Fan ChenInstitute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.
Hsin-You OuLiver Transplantation Program and Departments of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833401, Taiwan.ORCID 0000-0002-6992-6253
Keng-Hao LiuDepartment of Mechanical and Electro-Mechanical Engineering, National SunYat-sen University, Kaohsiung 80424, Taiwan.
Zhi-Yun LiDepartment of Mechanical and Electro-Mechanical Engineering, National SunYat-sen University, Kaohsiung 80424, Taiwan.
Chien-Chang LiaoLiver Transplantation Program and Departments of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833401, Taiwan.
Shao-Yu WangDepartment of Mechanical and Electro-Mechanical Engineering, National SunYat-sen University, Kaohsiung 80424, Taiwan.ORCID 0000-0003-3676-0004
Wen HuangDepartment of Mechanical and Electro-Mechanical Engineering, National SunYat-sen University, Kaohsiung 80424, Taiwan.
Yu-Fan ChengLiver Transplantation Program and Departments of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833401, Taiwan.
Cheng-Tang PanInstitute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.

Funding

Kaohsiung Chang Gung Memorial Hospital CMRPG8I0261
6 · The paper itself

Abstract

Cancer is one of the common diseases. Quantitative biomarkers extracted from standard-of-care computed tomography (CT) scan can create a robust clinical decision tool for the diagnosis of hepatocellular carcinoma (HCC). According to the current clinical methods, the situation usually accounts for high expenditure of time and resources. To improve the current clinical diagnosis and therapeutic procedure, this paper proposes a deep learning-based approach, called Successive Encoder-Decoder (SED), to assist in the automatic interpretation of liver lesion/tumor segmentation through CT images. The SED framework consists of two different encoder-decoder networks connected in series. The first network aims to remove unwanted voxels and organs and to extract liver locations from CT images. The second network uses the results of the first network to further segment the lesions. For practical purpose, the predicted lesions on individual CTs were extracted and reconstructed on 3D images. The experiments conducted on 4300 CT images and LiTS dataset demonstrate that the liver segmentation and the tumor prediction achieved 0.92 and 0.75 in Dice score, respectively, by as-proposed SED method.

Indexed as

3D segmentation displaydeep learninghepatocellular carcinomaliver lesion segmentationsuccessive Encoder-DecoderU-Net

Identifiers

PMID33374672
PMCPMC7822491

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.