Evidence map›Paper›PMID 33374623›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

Pharmacokinetics of Mephedrone Enantiomers in Whole Blood after a Controlled Intranasal Administration to Healthy Human Volunteers.

Joanna Czerwinska, Mark C Parkin, Agostino Cilibrizzi, Claire George, Andrew T Kicman, Paul I Dargan, Vincenzo Abbate

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Mephedrone and Its Metabolites: A Narrative Review.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Joanna CzerwinskaKing's Forensics, Department of Analytical, Environmental and Forensic Sciences, King's College London, London SE1 9NH, UK.
Mark C ParkinKing's Forensics, Department of Analytical, Environmental and Forensic Sciences, King's College London, London SE1 9NH, UK.
Agostino CilibrizziInstitute of Pharmaceutical Science, King's College London, London SE1 9NH, UK.ORCID 0000-0002-9711-5183
Claire GeorgeAlere Toxicology (Now Part of Abbott), Abingdon OX14 1DY, UK.
Andrew T KicmanKing's Forensics, Department of Analytical, Environmental and Forensic Sciences, King's College London, London SE1 9NH, UK.
Paul I DarganClinical Toxicology, Faculty of Life Sciences and Medicine, King's College London, London SE1 9NH, UK.
Vincenzo AbbateKing's Forensics, Department of Analytical, Environmental and Forensic Sciences, King's College London, London SE1 9NH, UK.ORCID 0000-0002-3300-0520
King's College London · GBAbbott (United Kingdom) · GB

Funding

Abbott N/ABiotechnology and Biological Sciences Research Council BB/M014940/1
6 · The paper itself

Abstract

Mephedrone, which is one of the most popular synthetic cathinones, has one chiral centre and thus exists as two enantiomers:

Indexed as

enantiomersintranasal administrationmephedronepharmacokineticswhole blood

Identifiers

PMID33374623
PMCPMC7822411
OpenAlexW3117119762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.