Evidence map›Paper›PMID 33374601›Full record

ArticleMembranes2020

Rifampicin-Loaded Alginate-Gelatin Fibers Incorporated within Transdermal Films as a

Ameya Sharma, Vivek Puri, Pradeep Kumar, Inderbir Singh

Open access · goldAbstract read
In one paragraph

Article in Membranes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 44 citations in OpenAlex.

  1. Dihydromyricetin-LoadedPharmaceutics · 2026
    Article
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  3. Review
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  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Polysaccharide-Based Transdermal Drug Delivery.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ameya SharmaChitkara College of Pharmacy, Chitkara University, Punjab 140401, India.ORCID 0000-0003-3810-4238
Vivek PuriChitkara College of Pharmacy, Chitkara University, Punjab 140401, India.ORCID 0000-0002-4497-9412
Pradeep KumarDepartment of Pharmacy and Pharmacology, Faculty of Health Sciences, School of Therapeutic, Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown 2193, South Africa.ORCID 0000-0002-8640-4350
Inderbir SinghChitkara College of Pharmacy, Chitkara University, Punjab 140401, India.
Chitkara University · INUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The various biological and molecular cascades including different stages or phases such as inflammation, tissue proliferation, and remodeling phases, which significantly define the wound healing process. The natural matrix system is suggested to increase and sustain these cascades. Biocompatible biopolymers, sodium alginate and gelatin, and a drug (Rifampicin) were used for the preparation of fibers into a physical crosslinking solution using extrusion-gelation. The formed fibers were then loaded in transdermal films for wound healing applications. Rifampicin, an antibiotic, antibacterial agent was incorporated into fibers and afterwards the fibers were loaded into transdermal films. Initially, rifampicin fibers were developed using biopolymers including alginate and gelatin, and were further loaded into polymeric matrix which led to the formation of transdermal films. The transdermal films were coded as TF1, TF2, TF3 and TF4.The characterization technique, FTIR, was used to describe molecular transitions within fibers, transdermal films, and was further corroborated using SEM and XRD. In mechanical properties, the parameters, such as tensile strength and elongation-at-break (extensibility), were found to be ranged between 2.32 ± 0.45 N/mm

Indexed as

alginatebiopolymersfibersgelatinrifampicintransdermal filmswound dressings

Identifiers

PMID33374601
PMCPMC7822433
OpenAlexW3115101357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.