Evidence map›Paper›PMID 33374564›Full record

ArticleCancers2020

Impact of Low-Dose Irradiation of the Lung and Heart on Toxicity and Pulmonary Function Parameters after Thoracic Radiotherapy.

Christina Schröder, André Buchali, Paul Windisch, Erwin Vu, Lucas Basler, Daniel R Zwahlen, Robert Förster

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. RUNX1 promotes NSCLC progression by ACP5/SMAD3-mediated M2 macrophage polarization.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Christina SchröderDepartment of Radiation Oncology, Ruppiner Kliniken GmbH, Medizinische Hochschule Brandenburg (MHB), Fehrbelliner Strasse 38, 16816 Neuruppin, Germany.
André BuchaliDepartment of Radiation Oncology, Ruppiner Kliniken GmbH, Medizinische Hochschule Brandenburg (MHB), Fehrbelliner Strasse 38, 16816 Neuruppin, Germany.
Paul WindischInstitute of Radiation Oncology, Cantonal Hospital Winterthur (KSW), Brauerstrasse 15, 8401 Winterthur, Switzerland.ORCID 0000-0003-1040-4888
Erwin VuDepartment of Radiation Oncology, Cantonal Hospital St. Gallen (KSSG), Rorschacher Strasse 95, 9007 St. Gallen, Switzerland.
Lucas BaslerCenter for Proton Therapy, Paul Scherrer Institute (PSI), ETH Domain, Forschungsstrasse 111, 5232 Villigen, Switzerland.ORCID 0000-0003-1259-5825
Daniel R ZwahlenInstitute of Radiation Oncology, Cantonal Hospital Winterthur (KSW), Brauerstrasse 15, 8401 Winterthur, Switzerland.ORCID 0000-0003-4359-7735
Robert FörsterInstitute of Radiation Oncology, Cantonal Hospital Winterthur (KSW), Brauerstrasse 15, 8401 Winterthur, Switzerland.ORCID 0000-0002-7664-9207
Board of the Swiss Federal Institutes of Technology · CHUniversity of Zurich · CHKantonsspital St. Gallen · CHKantonsspital Winterthur · CHMedizinische Hochschule Brandenburg Theodor Fontane · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the impact of (low) dose irradiation to the lungs and heart on the incidence of pneumonitis and pulmonary function changes after thoracic radiotherapy (RT). Methods/Material: Data of 62 patients treated with curative thoracic radiotherapy were analyzed. Toxicity data and pulmonary function tests (PFTs) were obtained before RT and at 6 weeks, at 12 weeks, and at 6 months after RT. PFTs included ventilation (e.g., vital capacity) and diffusion parameters (e.g., diffusion capacity for carbon monoxide (DL

resultsNo statistically significant correlations between dose parameters and changes in ventilation parameters were found. There were statistically significant correlations between DL

conclusionThere seems to be a lasting impact of low dose irradiation to the lung as well as irradiation to the heart on the DL

Indexed as

lung neoplasmsorgans at riskradiation injuriesrespiratory function tests

Identifiers

PMID33374564
PMCPMC7793060
OpenAlexW3118052429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.