Evidence map›Paper›PMID 33374463›Full record

ReviewFoods (Basel, Switzerland)2020

Food Bioactive Compounds and Emerging Techniques for Their Extraction: Polyphenols as a Case Study.

José S Câmara, Bianca R Albuquerque, Joselin Aguiar, Rúbia C G Corrêa, João L Gonçalves, Daniel Granato, Jorge A M Pereira, Lillian Barros, Isabel C F R Ferreira

Open access · goldAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
8.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 199 citations in OpenAlex.

  1. Review
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  11. Molecules (Basel, Switzerland) · 2025
    Review
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

José S CâmaraCQM-Centro de Química da Madeira, Campus Universitário da Penteada, Universidade da Madeira, 9020-105 Funchal, Portugal.ORCID 0000-0003-1965-3151
Bianca R AlbuquerqueCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0003-4109-7921
Joselin AguiarCQM-Centro de Química da Madeira, Campus Universitário da Penteada, Universidade da Madeira, 9020-105 Funchal, Portugal.
Rúbia C G CorrêaCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0003-0269-4344
João L GonçalvesCQM-Centro de Química da Madeira, Campus Universitário da Penteada, Universidade da Madeira, 9020-105 Funchal, Portugal.ORCID 0000-0002-1265-6686
Daniel GranatoFood Processing and Quality, Natural Resources Institute Finland (Luke), Tietotie 2, FI-02150 Espoo, Finland.ORCID 0000-0002-4533-1597
Jorge A M PereiraCQM-Centro de Química da Madeira, Campus Universitário da Penteada, Universidade da Madeira, 9020-105 Funchal, Portugal.ORCID 0000-0003-0316-5348
Lillian BarrosCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0002-9050-5189
Isabel C F R FerreiraCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0003-4910-4882
Universidade da Madeira · PTPolytechnic Institute of Bragança · PTCentro Universitário Cesumar · BRNatural Resources Institute Finland · FIUniversidade do Porto · PT

Funding

ARDITI - Agência Regional para o Desenvolvimento da Investigação Tecnologia e Inovação M1420-01-0145-FEDER-000005ARDITI - Agência Regional para o Desenvolvimento da Investigação Tecnologia e Inovação M1420 - 09-5369-FSE-000001Fundação para a Ciência e a Tecnologia SFRH/BD/116895/2016Fundação para a Ciência e a Tecnologia SFRH/BD/136370/2018Fundação para a Ciência e a Tecnologia UIDB/00674/2020Fundação para a Ciência e a Tecnologia UIDB/00690/2020Fundação para a Ciência e a Tecnologia UIDP/00674/2020Madeira 14-20 Program M1420-01-0145-FEDER-000008
6 · The paper itself

Abstract

Experimental studies have provided convincing evidence that food bioactive compounds (FBCs) have a positive biological impact on human health, exerting protective effects against non-communicable diseases (NCD) including cancer and cardiovascular (CVDs), metabolic, and neurodegenerative disorders (NDDs). These benefits have been associated with the presence of secondary metabolites, namely polyphenols, glucosinolates, carotenoids, terpenoids, alkaloids, saponins, vitamins, and fibres, among others, derived from their antioxidant, antiatherogenic, anti-inflammatory, antimicrobial, antithrombotic, cardioprotective, and vasodilator properties. Polyphenols as one of the most abundant classes of bioactive compounds present in plant-based foods emerge as a promising approach for the development of efficacious preventive agents against NCDs with reduced side effects. The aim of this review is to present comprehensive and deep insights into the potential of polyphenols, from their chemical structure classification and biosynthesis to preventive effects on NCDs, namely cancer, CVDs, and NDDS. The challenge of polyphenols bioavailability and bioaccessibility will be explored in addition to useful industrial and environmental applications. Advanced and emerging extraction techniques will be highlighted and the high-resolution analytical techniques used for FBCs characterization, identification, and quantification will be considered.

Indexed as

bioavailability and bioaccessibilitycancercardiovascular diseases (CVDs)disease protectionfood bioactive compounds (FBCs)neurodegenerative diseases (NDs)polyphenols

Identifiers

PMID33374463
PMCPMC7823739
OpenAlexW3117323139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.