Evidence map›Paper›PMID 33374308›Full record

ArticleInternational journal of molecular sciences2020

Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and P

Peter Franz, Wiebke Ewert, Matthias Preller, Georgios Tsiavaliaris

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Switch-2 determines MgFrontiers in physiology · 2024
    Article
  4. Review
  5. Background and roles: myosin in autoimmune diseases.Frontiers in cell and developmental biology · 2023
    Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Peter FranzCellular Biophysics, Institute for Biophysical Chemistry, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0001-9770-743X
Wiebke EwertStructural Bioinformatics and Chemical Biology, Institute for Biophysical Chemistry, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0001-8626-4864
Matthias PrellerStructural Bioinformatics and Chemical Biology, Institute for Biophysical Chemistry, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-7784-4012
Georgios TsiavaliarisCellular Biophysics, Institute for Biophysical Chemistry, Hannover Medical School, 30625 Hannover, Germany.
Medizinische Hochschule Hannover · DEHochschule Bonn-Rhein-Sieg · DE

Funding

Deutsche Forschungsgemeinschaft PR1478/2-1Deutsche Forschungsgemeinschaft TS169/5-1
6 · The paper itself

Abstract

The actomyosin system generates mechanical work with the execution of the power stroke, an ATP-driven, two-step rotational swing of the myosin-neck that occurs post ATP hydrolysis during the transition from weakly to strongly actin-bound myosin states concomitant with P

Indexed as

ActomyosinAdenosine DiphosphateAdenosine TriphosphateAllosteric RegulationDictyosteliumPhosphatesProtozoan ProteinsActomyosinAdenosine DiphosphateAdenosine TriphosphatePhosphatesProtozoan Proteinsactinallosteric communicationATPase cycleduty ratioforce generationmyosinpower stroketransient kinetics

Identifiers

PMID33374308
PMCPMC7795666
OpenAlexW3114562492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.