Evidence map›Paper›PMID 33374300›Full record

ArticleInternational journal of molecular sciences2020

Interplay between Thyroid Hormones and Stearoyl-CoA Desaturase 1 in the Regulation of Lipid Metabolism in the Heart.

Adam Olichwier, Volodymyr V Balatskyi, Marcin Wolosiewicz, James M Ntambi, Pawel Dobrzyn

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Role of Stearoyl-CoA Desaturase 1 in Cardiovascular Physiology.International journal of molecular sciences · 2023
    Review
  5. Article
  6. CoA in Health and Disease.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Adam OlichwierLaboratory of Molecular Medical Biochemistry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.
Volodymyr V BalatskyiLaboratory of Molecular Medical Biochemistry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.ORCID 0000-0002-9893-3049
Marcin WolosiewiczLaboratory of Molecular Medical Biochemistry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.
James M NtambiDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-9784-9550
Pawel DobrzynLaboratory of Molecular Medical Biochemistry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego · PLUniversity of Wisconsin–Madison · US

Funding

Narodowe Centrum Nauki UMO-2016/22/E/NZ4/00650, UMO-2014/13/B/NZ4/00199, UMO-2017/27/N/NZ4/01995
6 · The paper itself

Abstract

Stearoyl-CoA desaturase 1 (SCD1), an enzyme that is involved in the biosynthesis of monounsaturated fatty acids, induces the reprogramming of cardiomyocyte metabolism. Thyroid hormones (THs) activate both lipolysis and lipogenesis. Many genes that are involved in lipid metabolism, including

Indexed as

Down-RegulationGene Expression Regulation, EnzymologicLipid MetabolismAnimalsMiceMice, KnockoutMyocardiumStearoyl-CoA DesaturaseThyrotropinThyroxineScd1 protein, mouseStearoyl-CoA DesaturaseThyrotropinThyroxinehypothyroidisminflammationlipogenesislipolysisSCD1β-oxidation

Identifiers

PMID33374300
PMCPMC7796080
OpenAlexW3116416789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.