Evidence map›Paper›PMID 33374180›Full record

ArticleMolecules (Basel, Switzerland)2020

In Silico and In Vitro Analysis of Major Cannabis-Derived Compounds as Fatty Acid Amide Hydrolase Inhibitors.

Emanuele Criscuolo, Maria Laura De Sciscio, Filomena Fezza, Mauro Maccarrone

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Emanuele CriscuoloDepartment of Experimental Medicine, Tor Vergata University of Rome, Via Montpellier 1, 00121 Rome, Italy.
Maria Laura De SciscioDepartment of Medicine, Campus Bio-Medico University of Rome, Via Alvaro del Portillo 21, 00128 Rome, Italy.
Filomena FezzaDepartment of Experimental Medicine, Tor Vergata University of Rome, Via Montpellier 1, 00121 Rome, Italy.
Mauro MaccarroneDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio snc, 67100 L'Aquila, Italy.ORCID 0000-0002-3990-2963
University of Rome Tor Vergata · ITUniversità Campus Bio-Medico · ITUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulated evidence suggests that enhancing the endocannabinoid (eCB) tone, in particular of anandamide (

Indexed as

Models, MolecularAmidohydrolasesAmino Acid SequenceBinding SitesCannabisDose-Response Relationship, DrugEnzyme ActivationEnzyme InhibitorsFatty Acid Amide HydrolasesMolecular ConformationMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructurePhytochemicalsProtein BindingStructure-Activity RelationshipAmidohydrolasesEnzyme InhibitorsFatty Acid Amide HydrolasesPhytochemicalscannabinoidsdockingendocannabinoidsFAAHinhibitionmodeling

Identifiers

PMID33374180
PMCPMC7795171
OpenAlexW3117248279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.