Evidence map›Paper›PMID 33374179›Full record

ArticleInternational journal of molecular sciences2020

Development of New Antiproliferative Compound against Human Tumor Cells from the Marine Microalgae

Rafael Carrasco-Reinado, Almudena Escobar-Niño, Carlos Fajardo, Ines M Morano, Francisco Amil-Ruiz, Gonzalo Martinez-Rodríguez, Carlos Fuentes-Almagro, Victoria Capilla, Lidia Tomás-Cobos, Laura Soriano-Romaní and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Proteomic Approach toInternational journal of molecular sciences · 2023
    Article
  6. Article
  7. Anti-Steatotic Effects ofNutrients · 2023
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rafael Carrasco-ReinadoMicrobiology Laboratory, Institute of Viticulture and Agri-Food Research (IVAGRO), University of Cádiz, Pol. Río San Pedro s/n, 11510 Cádiz, Spain.
Almudena Escobar-NiñoMicrobiology Laboratory, Institute of Viticulture and Agri-Food Research (IVAGRO), University of Cádiz, Pol. Río San Pedro s/n, 11510 Cádiz, Spain.ORCID 0000-0001-5637-1474
Carlos FajardoMicrobiology Laboratory, Institute of Viticulture and Agri-Food Research (IVAGRO), University of Cádiz, Pol. Río San Pedro s/n, 11510 Cádiz, Spain.ORCID 0000-0001-9403-2211
Ines M MoranoMicrobiology Laboratory, Institute of Viticulture and Agri-Food Research (IVAGRO), University of Cádiz, Pol. Río San Pedro s/n, 11510 Cádiz, Spain.
Francisco Amil-RuizSCAI, University of Córdoba, Ramón y Cajal Building, Rabanales Campus, 14071 Córdoba, Spain.
Gonzalo Martinez-RodríguezInstitute of Marine Science of Andalusia, Spanish Council for Scientific Research, ICMAN-CSIC, 11510 Cádiz, Spain.ORCID 0000-0003-3379-580X
Carlos Fuentes-AlmagroSCAI, University of Córdoba, Ramón y Cajal Building, Rabanales Campus, 14071 Córdoba, Spain.
Victoria CapillaAINIA, Parque Tecnológico de Valencia, C.Benjamín Franklin 5-11, 46980 Paterna, Spain.
Lidia Tomás-CobosAINIA, Parque Tecnológico de Valencia, C.Benjamín Franklin 5-11, 46980 Paterna, Spain.
Laura Soriano-RomaníAINIA, Parque Tecnológico de Valencia, C.Benjamín Franklin 5-11, 46980 Paterna, Spain.ORCID 0000-0001-7513-9224
Palmira GuarnizoNeoALGAE Micro Seaweed Productos, Project Department, Planta I+D de Microalgas-UPT Litoral, Ctra. Faro Mesa Roldán s/n, 04140 Carboneras, Spain.
Roberto A VallejoResearch Project Manager of Innovation Department, Endesa Generación, S.A., Ribera del Loira 60, 28042 Madrid, Spain.
Francisco Javier Fernández-AceroMicrobiology Laboratory, Institute of Viticulture and Agri-Food Research (IVAGRO), University of Cádiz, Pol. Río San Pedro s/n, 11510 Cádiz, Spain.ORCID 0000-0002-4052-6141

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteomics is a crucial tool for unravelling the molecular dynamics of essential biological processes, becoming a pivotal technique for basic and applied research. Diverse bioinformatic tools are required to manage and explore the huge amount of information obtained from a single proteomics experiment. Thus, functional annotation and protein-protein interactions are evaluated in depth leading to the biological conclusions that best fit the proteomic response in the system under study. To gain insight into potential applications of the identified proteins, a novel approach named "Applied Proteomics" has been developed by comparing the obtained protein information with the existing patents database. The development of massive sequencing technology and mass spectrometry (MS/MS) improvements has allowed the application of proteomics nonmodel microorganisms, which have been deeply described as a novel source of metabolites. Between them,

Indexed as

AdenocarcinomaAntineoplastic AgentsCarcinoma, HepatocellularColonic NeoplasmsLiver NeoplasmsCaco-2 CellsCell ProliferationHep G2 CellsHumansMicroalgaeStramenopilesAntineoplastic Agentsapplied proteomicsbiomedicineindustrial applicationmicroalgaeproteintumor-antiproliferative

Identifiers

PMID33374179
PMCPMC7795124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.