Evidence map›Paper›PMID 33374161›Full record

ArticleMolecules (Basel, Switzerland)2020

Novel Polyhedral Silsesquioxanes [POSS(OH)

Kinga Piorecka, Jan Kurjata, Wlodzimierz A Stanczyk

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kinga PioreckaCentre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland.ORCID 0000-0002-7104-2959
Jan KurjataCentre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland.
Wlodzimierz A StanczykCentre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland.ORCID 0000-0002-9870-2232
Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk · PL

Funding

National Science Center UMO-2016/21/N/ST5/03360
6 · The paper itself

Abstract

Anthracyclines belong to the anticancer drugs that are widely used in chemotherapy. However, due to their systemic toxicity they also exert dangerous side effects associated mainly with cardiovascular risks. The pathway that is currently often developed is their chemical and physical modification via formation of conjugated or complexed prodrug systems with a variety of nanocarriers that can selectively release the active species in cancer cells. In this study, six new nanoconjugates were synthesized with the use of polyhedral oligosilsesquioxanes [POSS(OH)

Indexed as

AnthracyclinesAntineoplastic AgentsCell Line, TumorDrug CarriersDrug Delivery SystemsHumansHydrodynamicsMagnetic Resonance SpectroscopyMolecular StructureOrganosilicon CompoundsProdrugsSpectrum AnalysisAnthracyclinesAntineoplastic AgentsDrug CarriersOrganosilicon CompoundspolyhedraloligosilsesquioxaneProdrugsanthracyclinesanticancer conjugatespolyhedral oligomeric silsesquioxanes

Identifiers

PMID33374161
PMCPMC7794878
OpenAlexW3117202636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.