Evidence map›Paper›PMID 33374141›Full record

ArticleVaccines2020

Changes in Serum Biomarkers of Oxidative Stress in Cattle Vaccinated with Tick Recombinant Antigens: A Pilot Study.

Marinela Contreras, Camila Peres Rubio, José de la Fuente, Margarita Villar, Octavio Merino, Juan Mosqueda, José Joaquín Cerón

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Marinela ContrerasInterdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Campus of International Excellence Mare Nostrum, University of Murcia, Campus de Espinardo s/n, 30100 Murcia, Spain.
Camila Peres RubioInterdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Campus of International Excellence Mare Nostrum, University of Murcia, Campus de Espinardo s/n, 30100 Murcia, Spain.ORCID 0000-0002-9293-4147
José de la FuenteSaBio, Instituto de Investigación en Recursos Cinegéticos, IREC (CSIC-UCLM-JCCM), Ronda de Toledo 12, 13071 Ciudad Real, Spain.ORCID 0000-0001-7383-9649
Margarita VillarSaBio, Instituto de Investigación en Recursos Cinegéticos, IREC (CSIC-UCLM-JCCM), Ronda de Toledo 12, 13071 Ciudad Real, Spain.ORCID 0000-0003-4172-9079
Octavio MerinoFaculty of Veterinary Medicine, University of Tamaulipas, Tamaulipas 87000, Mexico.
Juan MosquedaFaculty of Veterinary Medicine, Autonomus University of Querétaro, Santiago de Querétaro 76010, Mexico.ORCID 0000-0001-8892-6390
José Joaquín CerónInterdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Campus of International Excellence Mare Nostrum, University of Murcia, Campus de Espinardo s/n, 30100 Murcia, Spain.
Universidad de Murcia · ESAutonomous University of Queretaro · MXInstituto de Investigación en Recursos Cinegéticos · ESOklahoma State University · US

Funding

Seneca Foundation-Regional Agency for Science and Technology of the Government of Murcia 19894/ GERM/15
6 · The paper itself

Abstract

Tick vaccination is an environmentally friendly alternative for tick control, pathogen infection, and transmission. Tick vaccine protection is sometimes incomplete, which may be due to problems in the stability, conformation, and activity of antibodies. This might be related to oxidative stress, but more studies are needed about the possible relationships between oxidative stress and immune function. The objective of this study was to evaluate and compare various serum biomarkers of antioxidant response and oxidative damage in cattle vaccinated with two recombinant antigens, the chimera of Subolesin- BM95 (homologue antigen of BM86)-MSP1a and BM86, and a control consisting in the adjuvant of the vaccines. Cupric reducing antioxidant capacity (CUPRAC), ferric reducing ability of the plasma (FRAP), trolox equivalent antioxidant capacity (TEAC), total thiol concentrations, and uric acid were evaluated in serum to determine the antioxidant response. To evaluate oxidative status, ferrous oxidation-xylenol orange (FOX), total oxidant status (TOS), advanced oxidation protein products (AOPP) and hydrogen peroxide (H

Indexed as

antibodyantioxidantbiomarkercattleoxidanttickvaccine

Identifiers

PMID33374141
PMCPMC7824418
OpenAlexW3113706031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.