Evidence map›Paper›PMID 33373972›Full record

ArticleComputerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society2021

Fully automated 3D segmentation of MR-imaged calf muscle compartments: Neighborhood relationship enhanced fully convolutional network.

Zhihui Guo, Honghai Zhang, Zhi Chen, Ellen van der Plas, Laurie Gutmann, Daniel Thedens, Peggy Nopoulos, Milan Sonka

Abstract read
In one paragraph

Article in Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhihui GuoIowa Institute for Biomedical Imaging, University of Iowa, Iowa City, IA 52242, USA. Electronic address: zhihui-guo@uiowa.edu.
Honghai ZhangIowa Institute for Biomedical Imaging, University of Iowa, Iowa City, IA 52242, USA.
Zhi ChenIowa Institute for Biomedical Imaging, University of Iowa, Iowa City, IA 52242, USA.
Ellen van der PlasDepartment of Psychiatry, University of Iowa, Iowa City, IA 52242, USA.
Laurie GutmannDepartment of Neurology, University of Iowa, Iowa City, IA 52242, USA.
Daniel ThedensDepartment of Psychiatry, University of Iowa, Iowa City, IA 52242, USA.
Peggy NopoulosDepartment of Psychiatry, University of Iowa, Iowa City, IA 52242, USA.
Milan SonkaIowa Institute for Biomedical Imaging, University of Iowa, Iowa City, IA 52242, USA.

Funding

Graph-Based Medical Image Segmentation in 3D and 4DR01EB004640 · NIBIB · UNIVERSITY OF IOWA · PI BUATTI, JOHN M, SONKA, MILAN · 2006 to 2022
$6.1M
Longitudinal Assessment of Brain Structure and Function in Myotonic DystrophyR01NS094387 · NINDS · UNIVERSITY OF IOWA · PI NOPOULOS, PEGGY C · 2015 to 2019
$4.1M
NIBIB NIH HHS R01 EB004640NINDS NIH HHS R01 NS094387
6 · The paper itself

Abstract

Automated segmentation of individual calf muscle compartments from 3D magnetic resonance (MR) images is essential for developing quantitative biomarkers for muscular disease progression and its prediction. Achieving clinically acceptable results is a challenging task due to large variations in muscle shape and MR appearance. In this paper, we present a novel fully convolutional network (FCN) that utilizes contextual information in a large neighborhood and embeds edge-aware constraints for individual calf muscle compartment segmentations. An encoder-decoder architecture is used to systematically enlarge convolution receptive field and preserve information at all resolutions. Edge positions derived from the FCN output muscle probability maps are explicitly regularized using kernel-based edge detection in an end-to-end optimization framework. Our method was evaluated on 40 T1-weighted MR images of 10 healthy and 30 diseased subjects by fourfold cross-validation. Mean DICE coefficients of 88.00-91.29% and mean absolute surface positioning errors of 1.04-1.66 mm were achieved for the five 3D muscle compartments.

Indexed as

Image Processing, Computer-AssistedNeural Networks, ComputerHumansLegMagnetic Resonance ImagingMuscles3DCalf muscle compartment segmentationEdge constraintFully convolutional networkMagnetic resonance image

Identifiers

PMID33373972
PMCPMC7855601

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.