Evidence map›Paper›PMID 33373644›Full record

ArticleJournal of molecular and cellular cardiology2021

Pathophysiology and pharmacological management of pulmonary and cardiovascular features of COVID-19.

Walid Hamouche, Malik Bisserier, Agnieszka Brojakowska, Abrisham Eskandari, Kenneth Fish, David A Goukassian, Lahouaria Hadri

Abstract read
In one paragraph

Article in Journal of molecular and cellular cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. COVID-19's immuno-pathology and cardiovascular diseases.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2023
    Review
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Walid HamoucheCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Internal Medicine Department, Brookdale University Hospital Medical Center, Brooklyn, NY, USA.
Malik BisserierCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Agnieszka BrojakowskaCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Abrisham EskandariCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kenneth FishCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
David A GoukassianCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lahouaria HadriCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: Lahouaria.hadri@mssm.edu.

Funding

TRAINING PROGRAM IN MOLECULAR AND CELLULAR CARDIOLOGYT32HL007824 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GELB, BRUCE D · 1995 to 2022
$8.6M
Interactions of SERCA2a and BMPRII in Vascular DiseaseR01HL133554 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HADRI, LAHOUARIA · 2016 to 2020
$2.3M
Role of Epac1 in the Pathogenesis of Pulmonary FibrosisR01HL158998 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Lahouaria HADRI · 2022 to 2026
$2.1M
NHLBI NIH HHS R01 HL133554NHLBI NIH HHS R01 HL158998NHLBI NIH HHS T32 HL007824
6 · The paper itself

Abstract

The first confirmed case of novel Coronavirus Disease 2019 (COVID-19) in the United States was reported on January 20, 2020. As of November 24, 2020, close to 12.2 million cases of COVID-19 was confirmed in the US, with over 255,958 deaths. The rapid transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), its unusual and divergent presentation has strengthened the status of COVID-19 as a major public health threat. In this review, we aim to 1- discuss the epidemiological data from various COVID-19 patient cohorts around the world and the USA as well the associated risk factors; 2- summarize the pathophysiology of SARS-CoV-2 infection and the underlying molecular mechanisms for the respiratory and cardiovascular manifestations; 3- highlight the potential treatments and vaccines as well as current clinical trials for COVID-19.

Indexed as

Cardiovascular DiseasesCOVID-19Disease ManagementGlobal HealthHumansLung DiseasesSARS-CoV-2United StatesClinical featuresCOVID-19PhysiopathologyTreatment

Identifiers

PMID33373644
PMCPMC7833205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.