Observational studyPloS one2020
Association between platelet distribution width and prognosis in patients with heart failure.
Observational study in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Platelet indices and incident CKD in high-risk individuals.Clinical and experimental nephrology · 2026Article
- Prognostic impact of platelet count trajectories in acute decompensated heart failure: a retrospective cohort analysis.BMC cardiovascular disorders · 2026Article
- HearteXplain: explainable prediction of acute heart failure and identification of hematologic biomarkers using EBMs and Morris sensitivity analysis.Scientific reports · 2025Article
- Indications of platelet indices in coronary artery disease (CAD): more insights into their diagnostic and prognostic importance.Journal of thrombosis and thrombolysis · 2025Review
- Clonal haematopoiesis associates with distinct cytometric changes of red blood cells and platelets.British journal of haematology · 2025Article
- Article
- Association of Premature Ventricular Contraction (PVC) with hematological parameters: a data mining approach.Scientific reports · 2025Article
- Prognostic value of platelet volume indices in heart failure: a systematic review and meta-analysis.American journal of blood research · 2025Review
- The relationship of platelet distribution width with all-cause and cardiovascular mortality in peritoneal dialysis patients.Renal failure · 2024Article
- Predictors and Prognostic Factors of Heart Failure with Improved Ejection Fraction.Reviews in cardiovascular medicine · 2024Article
- The Role of Platelet Distribution Width in the Association Between Blood Glucose and Neurological Impairment Severity in Acute Ischemic Stroke: A Moderated Mediation Model.Journal of inflammation research · 2024Article
- Comparison of the effects of long-lasting static stretching and hypertrophy training on maximal strength, muscle thickness and flexibility in the plantar flexors.European journal of applied physiology · 2023Article
- One-year rehospitalisation and mortality after acute heart failure hospitalisation: a competing risk analysis.Open heart · 2023Observational
- Investigation of red blood cell and platelet indices in adult dogs suffered from myxomatous mitral valve disease with and without pulmonary hypertension.Frontiers in veterinary science · 2023Article
- The relationship between platelet distribution width and new-onset cardiovascular disease events in patients with peritoneal dialysis.Renal failure · 2022Article
- High platelet distribution width is an independent risk factor of postoperative pneumonia in patients with type A acute aortic dissection.Frontiers in cardiovascular medicine · 2022Article
- Predictive Biomarkers for Postmyocardial Infarction Heart Failure Using Machine Learning: A Secondary Analysis of a Cohort Study.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Platelet distribution width-a prognosis marker in patients with chronic heart failure.Porto biomedical journalArticle
- Do Mean Platelet Volume and Platelet Distribution Width Have An Association with White Matter Hyperintensities in Migraine Patients?Annals of Indian Academy of NeurologyArticle
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prognostic impact of platelet distribution width (PDW), which is a specific marker of platelet activation, has been unclear in patients with heart failure (HF). METHODS AND
resultsWe conducted a prospective observational study enrolling 1,746 hospitalized patients with HF. Patients were divided into tertiles based on levels of PDW: 1st (PDW < 15.9 fL, n = 586), 2nd (PDW 15.9-16.8 fL, n = 617), and 3rd (PDW ≥ 16.9, n = 543) tertiles. We compared baseline patients' characteristics and post-discharge prognosis: all-cause death; cardiac death; and cardiac events. The 3rd tertile showed the highest age and levels of B-type natriuretic peptide compared to other tertiles (1st, 2nd, and 3rd tertiles; age, 69.0, 68.0, and 70.0 years old, P = 0.038; B-type natriuretic peptide, 235.2, 171.9, and 241.0 pg/mL, P < 0.001). Left ventricular ejection fraction was equivalent among the tertiles. In the Kaplan-Meier analysis, rates of all endpoints were the highest in the 3rd tertile (log-rank P < 0.001, respectively). The Cox proportional hazard analysis revealed that the 3rd tertile was associated with adverse prognosis (all-cause death, hazard ratio [HR] 1.716, P < 0.001; cardiac death, HR 1.919, P < 0.001; cardiac event, HR 1.401, P = 0.002).
conclusionsHigh PDW is a novel predictor of adverse prognosis in patients with HF.
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