Evidence map›Paper›PMID 33373400›Full record

ArticlePloS one2020

Automatically detecting bregma and lambda points in rodent skull anatomy images.

Peng Zhou, Zheng Liu, Hemmings Wu, Yuli Wang, Yong Lei, Shiva Abbaszadeh

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. AUTOMATED VENTRICLE PARCELLATION AND EVAN'S RATIO COMPUTATION IN PRE- AND POST-SURGICAL VENTRICULOMEGALY.Proceedings. IEEE International Symposium on Biomedical Imaging · 2023
    Article
  2. Article
  3. Article
  4. Investigation of probability maps in deep-learning-based brain ventricle parcellation.Proceedings of SPIE--the International Society for Optical Engineering · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Peng ZhouDepartment of Electrical and Computer Engineering, University of California, Santa Cruz, Santa Cruz, California, United States of America.
Zheng LiuDepartment of Nuclear, Plasma, and Radiological Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.
Hemmings WuDepartment of Neurosurgery, Stanford University, Palo Alto, California, United States of America.
Yuli WangDepartment of Electrical and Computer Engineering, University of California, Santa Cruz, Santa Cruz, California, United States of America.ORCID 0000-0003-3311-2810
Yong LeiState Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University, Hangzhou, China.
Shiva AbbaszadehDepartment of Electrical and Computer Engineering, University of California, Santa Cruz, Santa Cruz, California, United States of America.ORCID 0000-0001-6345-2408
University of California, Santa Cruz · USStanford University · USUniversity of Illinois Urbana-Champaign · USZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, injection sites of probes, cannula, and optic fibers in stereotactic neurosurgery are typically located manually. This step involves location estimations based on human experiences and thus introduces errors. In order to reduce localization error and improve repeatability of experiments and treatments, we investigate an automated method to locate injection sites. This paper proposes a localization framework, which integrates a region-based convolutional network and a fully convolutional network, to locate specific anatomical points on skulls of rodents. Experiment results show that the proposed localization framework is capable of identifying and locatin bregma and lambda in rodent skull anatomy images with mean errors less than 300 μm. This method is robust to different lighting conditions and mouse orientations, and has the potential to simplify the procedure of locating injection sites.

Indexed as

AnimalsFemaleImage Processing, Computer-AssistedMaleMiceModels, AnimalNeural Networks, ComputerSkullStereotaxic Techniques

Identifiers

PMID33373400
PMCPMC7771702
OpenAlexW3115303948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.