Evidence map›Paper›PMID 33373269›Full record

ArticleThe Journal of international medical research2020

Clinicopathological features and differential diagnosis of gastrofibromatosis-like undifferentiated carcinoma.

Zhishang Zhang, Guang Zhao, Bo Jiang, Baohui Li, Yangkun Wang

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Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Zhishang ZhangDepartment of Pathology, Shenzhen Hospital of Southern Medical University, Shenzhen, China.
Guang ZhaoDepartment of Central Laboratory, The 989 Hospital of the Joint Logistic Support Force of the PLA, Luoyang, China.
Bo JiangDepartment of Pathology, The 990 Hospital of the Joint Logistic Support Force of the PLA, Zhumadian, China.
Baohui LiDepartment of Central Laboratory, The 989 Hospital of the Joint Logistic Support Force of the PLA, Luoyang, China.
Yangkun WangDepartment of Pathology, Shenzhen Hospital of Southern Medical University, Shenzhen, China.ORCID https://orcid.org/0000-0002-5664-058X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the clinicopathological features and differential diagnosis of gastrofibromatosis-like undifferentiated carcinoma (GFLUC).

methodsThree patients with GFLUC underwent histological and immunophenotypic analyses and fluorescence

resultsAmong the three patients (2 male [36 and 44 years old], 1 female [58 years old]), two had lesions in the gastric body and one had lesions in the gastric antrum. Histological analysis revealed mixtures of aggressive fibromatosis and undifferentiated carcinoma in all three cases. Highly invasive fibromatous tissue, consisting of fibroblasts, proliferating myofibroblasts, and collagenous fibrous tissues, accounted for >90% of the tumor, with undifferentiated cancerous tissue accounting for <10% scattered in the gaps within the invasive fibromatous tissue, with no glandular ducts or nests. Immunophenotypic analysis showed that the undifferentiated cancerous cells were positive for pan-cytokeratin, CDX2, villin, and p53, while the cytoplasm of invasive fibromatous cells was positive for vimentin, β-catenin, and smooth muscle actin. No

conclusionsUnlike other gastric carcinomas, GFLUC shows specific histological, biological, and immunophenotypic characteristics.

Indexed as

CarcinomaAdultBiomarkers, TumorDiagnosis, DifferentialErb-b2 Receptor Tyrosine KinasesErbB ReceptorsFemaleHumansImmunohistochemistryIn Situ Hybridization, FluorescenceMaleMiddle AgedBiomarkers, TumorErb-b2 Receptor Tyrosine KinasesErbB Receptorsdifferential diagnosisfibromatosis-like undifferentiated carcinomaGastric carcinomaHER2 genehistological featureimmunohistochemistry

Identifiers

PMID33373269
PMCPMC7783894

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.