Evidence map›Paper›PMID 33373215›Full record

ArticleJournal of the American Chemical Society2021

Samuel I Mann, Animesh Nayak, George T Gassner, Michael J Therien, William F DeGrado

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Review
  2. Review
  3. Next Generation Hosts for Protein Recognition, Assembly and More.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  4. AbioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. From single step hops to emergent biological phenomena.Journal of inorganic biochemistry · 2026
    Review
  10. Article
  11. Protein engineering: status report.Protein engineering, design & selection : PEDS · 2026
    Review
  12. Article
  13. Article
  14. bioRxiv : the preprint server for biology · 2025
    Article
  15. A Designed ZnJournal of the American Chemical Society · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Design of a light and CaProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samuel I MannDepartment of Pharmaceutical Chemistry and the Cardiovascular Research Institute, University of California at San Francisco, San Francisco, California 94158-9001, United States.ORCID 0000-0003-3392-3170
Animesh NayakDepartment of Chemistry, Duke University, Durham, North Carolina 27708, United States.
George T GassnerDepartment of Chemistry and Biochemistry, San Francisco State University, San Francisco, California 94132, United States.
Michael J TherienDepartment of Chemistry, Duke University, Durham, North Carolina 27708, United States.ORCID 0000-0003-4876-0036
William F DeGradoDepartment of Pharmaceutical Chemistry and the Cardiovascular Research Institute, University of California at San Francisco, San Francisco, California 94158-9001, United States.ORCID 0000-0003-4745-263X

Funding

De Novo Design of Functional Metalloporphyrin-Containing ProteinsF32GM130029 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MANN, SAMUEL I · 2018 to 2021
$178k
NIGMS NIH HHS F32 GM130029
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amino Acid SequenceCrystallography, X-RayHemeproteinsManganeseMetalloporphyrinsOxidation-ReductionProtein BindingProtein EngineeringSulfidesHemeproteinsManganeseMetalloporphyrinsmethylphenylsulfideSulfides

Identifiers

PMID33373215
PMCPMC8006777

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.