Evidence map›Paper›PMID 33372843›Full record

SynthesisVirulence2021

A systematic review of the epidemiology of Hepatitis E virus infection in South - Eastern Asia.

Yakubu Egigogo Raji, Ooi Peck Toung, Niazlin Mohd Taib, Zamberi Bin Sekawi

Abstract readSystematic Review
In one paragraph

Synthesis in Virulence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Traveling with chronic viral hepatitis.Tropical diseases, travel medicine and vaccines · 2026
    Review
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  5. Article
  6. Review
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  15. Review
  16. Discovering disease-causing pathogens in resource-scarce Southeast Asia using a global metagenomic pathogen monitoring system.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Article
  18. Article
  19. First Report of the HEV Seroprevalence and the Risk Factor Assessment in the West Bank, Palestine, during the Period of 2015-2017.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yakubu Egigogo RajiDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia 1 , Malaysia.ORCID 0000-0002-6231-1686
Ooi Peck ToungDepartment of Veterinary Clinical Studies Faculty of Veterinary Medicine, Universiti Putra Malaysia 2 , Malaysia.ORCID 0000-0002-1174-0288
Niazlin Mohd TaibDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia 1 , Malaysia.ORCID 0000-0002-9910-9393
Zamberi Bin SekawiDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia 1 , Malaysia.ORCID 0000-0002-5387-9640

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis E virus (HEV) infection is an emerging zoonotic viral disease, with an increasingly international public health challenge. Despite the concerns that the global disease burden may be underestimated. Therefore, evaluation of the disease epidemiology in South - eastern Asia through a systematic review will assist in unraveling the burden of the disease in the subregion. A priori protocol was prepared for the systematic review and followed by a literature search involving five electronic databases. Identified publications were screened for high quality studies and the elimination of bias and relevant data extracted. A total of 4157 citations were captured, and only 35 were included in the review. A wide range of HEV seroprevalence was recorded from 2% (urban blood donors in Malaysia) to 77.7% (lowland communities in Lao PDR). Sporadic HEV infection and epidemics were also detected in the subregion. Indicating hyperendemicity of the disease in South - eastern Asia.

Indexed as

Blood DonorsAsia, EasternHepatitis EHepatitis E virusHumansPrevalenceSeroepidemiologic StudiesHepatitis EHepatitis E virusHEV outbreaksseroprevalenceSouth – eastern Asiasporadic HEV infection

Identifiers

PMID33372843
PMCPMC7781573

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.