Evidence map›Paper›PMID 33372813›Full record

ArticleThe Journal of international medical research2020

Exploring the role of the complement system, endothelial injury, and microRNAs in thrombotic microangiopathy after kidney transplantation.

Andreja Aleš Rigler, Željka Večerić-Haler, Miha Arnol, Martina Perše, Emanuela Boštjančič, Jerica Pleško, Saša Simčič, Nika Kojc

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Andreja Aleš RiglerDepartment of Nephrology, University Medical Centre Ljubljana, Slovenia.
Željka Večerić-HalerDepartment of Nephrology, University Medical Centre Ljubljana, Slovenia.
Miha ArnolDepartment of Nephrology, University Medical Centre Ljubljana, Slovenia.
Martina PeršeMedical Experimental Centre, Faculty of Medicine, University of Ljubljana, Slovenia.
Emanuela BoštjančičInstitute of Pathology, Faculty of Medicine, University of Ljubljana, Slovenia.
Jerica PleškoInstitute of Pathology, Faculty of Medicine, University of Ljubljana, Slovenia.
Saša SimčičInstitute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Slovenia.
Nika KojcInstitute of Pathology, Faculty of Medicine, University of Ljubljana, Slovenia.ORCID https://orcid.org/0000-0003-1893-4349
University of Ljubljana · SILjubljana University Medical Centre · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe investigated whether the recipient's complement system function, kidney graft endothelial ultrastructural injury, and microRNA (miRNA) expression before transplantation may be associated with the risk of posttransplant

methodsComplement system function assessment, histological and ultrastructural examination of preimplantation and kidney graft biopsies, and microRNA assessment were performed on kidney transplant recipients (KTRs) with

resultsOn the basis of the clinical course, histological findings, and miRNA patterns, the following two

conclusionsAlternative complement pathway abnormalities in KTRs and endothelial ultrastructural injury on preimplantation biopsy might be associated with

Indexed as

Kidney TransplantationMicroRNAsThrombotic MicroangiopathiesBiopsyHumansKidneyMicroRNAsComplementcomplement dysregulationendothelial injurykidney transplantationmicroRNAthrombotic microangiopathy

Identifiers

PMID33372813
PMCPMC7783899
OpenAlexW3117501089

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.