Trial reportBMC oral health2020
Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy: a randomized clinical trial.
Trial report in BMC oral health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- The efficacy of subgingival air polishing and subgingival debridement in periodontal support therapy: a meta-analysis.Evidence-based dentistry · 2023Pooled it
- Effectiveness and Clinical Performance of Erythritol Air-Polishing in Non-Surgical Periodontal Therapy: A Systematic Review of Randomized Clinical Trials.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Analysis of the factors influencing the occurrence of peri-implantitis in patients with implant-supported restoration and study on the maintenance effect of subgingival sandblasting.BMC oral health · 2025Trial
- Airflowing as an adjunctive treatment for periodontitis: A randomized controlled trial.Journal of periodontology · 2024Trial
- Clinical evaluation of a novel protocol for supportive periodontal care: A randomized controlled clinical trial.Journal of periodontology · 2024Trial
- Guided biofilm therapy versus conventional protocol-clinical outcomes in non-surgical periodontal therapy.BMC oral health · 2024Trial
- The efficacy of diode laser and subgingival air polishing with erythritol in treatment of periodontitis (clinical and microbiological study).BMC oral health · 2024Trial
- Non-surgical treatment of peri-implantitis with and without erythritol air-polishing a 12-month randomized controlled trial.BMC oral health · 2023Trial
- The effectiveness of scaling and root planing with combined application of air polishing and Nd:YAG laser in periodontal pockets of stage III grade C periodontitis patients: a single-blinded randomized clinical trial.Clinical oral investigations · 2022Trial
- The efficacy of the adjunct use of subgingival air-polishing therapy with erythritol powder compared to conventional debridement alone during initial non-surgical periodontal therapy.Journal of clinical periodontology · 2022Trial
- Erythritol air polishing in the surgical treatment of peri-implantitis: A randomized controlled trial.Clinical oral implants research · 2022Trial
- Antimicrobial Efficacy and Soft-Tissue Safety of Air-Polishing Powders in Periodontal Therapy: A Narrative Review.Journal of functional biomaterials · 2025Review
- Comment on Onisor et al. Reply to Stein, J.M. Comment on "Onisor et al. Effectiveness and Clinical Performance of Erythritol Air-Polishing in Non-Surgical Periodontal Therapy: A Systematic Review of Randomized Clinical Trials.Medicina (Kaunas, Lithuania) · 2025Article
- Clinical Comparison of Guided Biofilm Therapy and Scaling and Root Planing in the Active Phase of Periodontitis Management.European journal of dentistry · 2025Article
- Subgingival Use of Air-Polishing Powders: Status of Knowledge: A Systematic Review.Journal of clinical medicine · 2023Review
- Clinical Trial for Evaluating the Effectiveness and Safety of a New Dental Plaque Removal Device: Microscale Mist Unit.Antibiotics (Basel, Switzerland) · 2022Article
- Nonsurgical Periodontal Treatment Options and Their Impact on Subgingival Microbiota.Journal of clinical medicine · 2022Article
- Novel Approach to Dental Biofilm Management through Guided Biofilm Therapy (GBT): A Review.Microorganisms · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study was aimed to investigate if the adjunctive use of erythritol air-polishing powder applied with the nozzle-system during subgingival instrumentation (SI) has an effect on the outcome of non-surgical periodontal treatment in patients with moderate to severe periodontitis.
methodsFourty-two individuals with periodontitis received nonsurgical periodontal therapy by SI without (controls, n = 21) and with adjunctive air-polishing using nozzle + erythritol powder (test, n = 21). They were analyzed for the clinical variables BOP (primary outcome at six months), probing depth (PD), attachment level, four selected microorganisms and two biomarkers at baseline, before SI as well as three and six months after SI. Statistical analysis included nonparametric tests for intra- and intergroup comparisons.
resultsIn both groups, the clinical variables PD, attachment level and BOP significantly improved three and six months after SI. The number of sites with PD ≥ 5 mm was significantly lower in the test group than in the control group after six months. At six months versus baseline, there were significant reductions of Tannerella forsythia and Treponema denticola counts as well as lower levels of MMP-8 in the test group.
conclusionsSubgingival instrumentation with adjunctive erythritol air-polishing powder does not reduce BOP. But it may add beneficial effects like reducing the probing depth measured as number of residual periodontal pocket with PD ≥ 5 mm when compared with subgingival instrumentation only. CLINICAL RELEVANCE: The adjunctive use of erythritol air-polishing powder applied with the nozzle-system during SI may improve the clinical outcome of SI and may reduce the need for periodontal surgery. Trial registration The study was retrospectively registered in the German register of clinical trials, DRKS00015239 on 6th August 2018, https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.