Evidence map›Paper›PMID 33372541›Full record

Observational studyJournal of the American Heart Association2021

Impact of Blood Pressure Visit-to-Visit Variability on Adverse Events in Patients With Nonvalvular Atrial Fibrillation: Subanalysis of the J-RHYTHM Registry.

Eitaro Kodani, Hiroshi Inoue, Hirotsugu Atarashi, Ken Okumura, Takeshi Yamashita, Toshiaki Otsuka, Hideki Origasa, J‐RHYTHM Registry Investigators *

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Systolic blood pressure visit-to-visit variability and outcomes in Asian patients with atrial fibrillation.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  7. Is atrial fibrillation a suitable target for studies on blood pressure variability?Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Eitaro KodaniDepartment of Internal Medicine and Cardiology Nippon Medical School Tama-Nagayama Hospital Tokyo Japan.
Hiroshi InoueSaiseikai Toyama Hospital Toyama Japan.
Hirotsugu AtarashiMinami-Hachioji Hospital Tokyo Japan.
Ken OkumuraSaiseikai Kumamoto Hospital Kumamoto Japan.
Takeshi YamashitaThe Cardiovascular Institute Tokyo Japan.
Toshiaki OtsukaDepartment of Hygiene and Public Health Nippon Medical School Tokyo Japan.
Hideki OrigasaDivision of Biostatistics and Clinical Epidemiology University of Toyama Japan.
J‐RHYTHM Registry Investigators *
University of Toyama · JPCardiovascular Institute Hospital · JPOtsuka (Japan) · JPSaiseikai Kumamoto Hospital · JPToyama University Hospital · JPNippon Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Blood pressure (BP) variability has reportedly been a risk factor for various clinical events. To clarify the influence of BP visit-to-visit variability on adverse events in patients with nonvalvular atrial fibrillation, a post hoc analysis of the J-RHYTHM Registry was performed. Methods and Results Of 7406 outpatients with nonvalvular atrial fibrillation from 158 institutions, 7226 (age, 69.7±9.9 years; men, 70.7%), in whom BP was measured 4 times or more (14.6±5.0 times) during the 2-year follow-up period or until occurrence of an event, constituted the study group. SD and coefficient of variation of BP values were calculated as BP variability. Thromboembolism, major hemorrhage, and all-cause death occurred in 110 (1.5%), 121 (1.7%), and 168 (2.3%) patients, respectively. When patients were divided into quartiles of systolic BP-SD (<8.20, 8.20-10.49, 10.50-13.19, and ≥13.20 mm Hg), hazard ratios (HRs) for all adverse events were significantly high in the highest quartile compared with the lowest quartile (HR, 2.00, 95% CI, 1.15-3.49,

Indexed as

Ambulatory CareAtrial FibrillationBlood Pressure DeterminationHemorrhagePlatelet Aggregation InhibitorsThromboembolismWarfarinAgedAnalysis of VarianceAnticoagulantsCause of DeathFemaleHumansJapanMaleRegistriesAnticoagulantsPlatelet Aggregation InhibitorsWarfarinatrial fibrillationblood pressuremajor hemorrhagethromboembolismvariability

Identifiers

PMID33372541
PMCPMC7955501
OpenAlexW3115528662

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.