Evidence map›Paper›PMID 33372531›Full record

Observational studyJournal of the American Heart Association2021

Five-Year Risk of Acute Myocardial Infarction After Acute Ischemic Stroke in Korea.

Keon-Joo Lee, Seong-Eun Kim, Jun Yup Kim, Jihoon Kang, Beom Joon Kim, Moon-Ku Han, Kang-Ho Choi, Joon-Tae Kim, Dong-Ick Shin, Jae-Kwan Cha and 28 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

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  7. Low-dose Rivaroxaban: is it a safe alternative in Chinese older patients?European journal of clinical pharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 16 institutions in 2 countries.

Keon-Joo LeeDepartment of Neurology and Cerebrovascular Center Seoul National University Bundang HospitalSeoul National University College of Medicine Seongnam Republic of Korea.
Seong-Eun KimDepartment of Neurology and Cerebrovascular Center Seoul National University Bundang HospitalSeoul National University College of Medicine Seongnam Republic of Korea.
Jun Yup KimDepartment of Neurology and Cerebrovascular Center Seoul National University Bundang HospitalSeoul National University College of Medicine Seongnam Republic of Korea.
Jihoon KangDepartment of Neurology and Cerebrovascular Center Seoul National University Bundang HospitalSeoul National University College of Medicine Seongnam Republic of Korea.
Beom Joon KimDepartment of Neurology and Cerebrovascular Center Seoul National University Bundang HospitalSeoul National University College of Medicine Seongnam Republic of Korea.
Moon-Ku HanDepartment of Neurology and Cerebrovascular Center Seoul National University Bundang HospitalSeoul National University College of Medicine Seongnam Republic of Korea.
Kang-Ho ChoiDepartment of Neurology Chonnam National University Hospital Gwangju Republic of Korea.
Joon-Tae KimDepartment of Neurology Chonnam National University Hospital Gwangju Republic of Korea.
Dong-Ick ShinDepartment of Neurology Chungbuk National University Hospital Cheongju Republic of Korea.
Jae-Kwan ChaDepartment of Neurology Dong-A University HospitalDong-A University College of Medicine Busan Republic of Korea.
Dae-Hyun KimDepartment of Neurology Dong-A University HospitalDong-A University College of Medicine Busan Republic of Korea.
Dong-Eog KimDepartment of Neurology Dongguk University Ilsan Hospital Goyang Republic of Korea.
Wi-Sun RyuDepartment of Neurology Dongguk University Ilsan Hospital Goyang Republic of Korea.
Jong-Moo ParkDepartment of Neurology Eulji General Hospital Seoul Republic of Korea.
Kyusik KangDepartment of Neurology Eulji General Hospital Seoul Republic of Korea.
Jae Guk KimDepartment of Neurology Eulji University HospitalEulji University Daejeon Republic of Korea.
Soo Joo LeeDepartment of Neurology Eulji University HospitalEulji University Daejeon Republic of Korea.
Mi-Sun OhDepartment of Neurology Hallym University Sacred Heart Hospital Anyang Republic of Korea.
Kyung-Ho YuDepartment of Neurology Hallym University Sacred Heart Hospital Anyang Republic of Korea.
Byung-Chul LeeDepartment of Neurology Hallym University Sacred Heart Hospital Anyang Republic of Korea.
Hong-Kyun ParkDepartment of Neurology Ilsan Paik HospitalInje University Goyang Republic of Korea.
Keun-Sik HongDepartment of Neurology Ilsan Paik HospitalInje University Goyang Republic of Korea.
Yong-Jin ChoDepartment of Neurology Ilsan Paik HospitalInje University Goyang Republic of Korea.
Jay Chol ChoiDepartment of Neurology Jeju National University HospitalJeju National University School of Medicine Jeju Republic of Korea.
Sung Il SohnDepartment of Neurology Keimyung University Dongsan Medical Center Daegu Republic of Korea.
Jeong-Ho HongDepartment of Neurology Keimyung University Dongsan Medical Center Daegu Republic of Korea.
Moo-Seok ParkDepartment of Neurology Seoul Medical Center Seoul Republic of Korea.
Tai Hwan ParkDepartment of Neurology Seoul Medical Center Seoul Republic of Korea.
Sang-Soon ParkDepartment of Neurology Seoul Medical Center Seoul Republic of Korea.
Kyung Bok LeeDepartment of Neurology College of Medicine Soonchunhyang University Hospital Seoul Republic of Korea.
Jee-Hyun KwonDepartment of Neurology Ulsan University HospitalUlsan University College of Medicine Ulsan Republic of Korea.
Wook-Joo KimDepartment of Neurology Ulsan University HospitalUlsan University College of Medicine Ulsan Republic of Korea.
Jun LeeDepartment of Neurology Yeungnam University Hospital Daegu Republic of Korea.
Ji Sung LeeClinical Research Center Asan Medical Center Seoul Republic of Korea.
Juneyoung LeeDepartment of Biostatistics Korea University College of Medicine Seoul Republic of Korea.
Philip B GorelickDavee Department of Neurology Feinberg School of Medicine Chicago IL.
Hee-Joon BaeDepartment of Neurology and Cerebrovascular Center Seoul National University Bundang HospitalSeoul National University College of Medicine Seongnam Republic of Korea.
CRCS‐K Registry Investigators
Seoul National University Bundang Hospital · KRDong-A University Hospital · KRHallym University Sacred Heart Hospital · KRInje University Ilsan Paik Hospital · KRKorea University · KRSeoul Medical Center · KREulji Medical Center · KRKeimyung University Dongsan Medical Center · KRSoonchunhyang University Hospital Seoul · KRUlsan University Hospital · KRChonnam National University Hospital · KRChungbuk National University Hospital · KRDaejeon Eulji Medical Center, Eulji University · KRDongguk University Ilsan Hospital · KRJeju National University Hospital · KRMichigan State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The long-term incidence of acute myocardial infarction (AMI) in patients with acute ischemic stroke (AIS) has not been well defined in large cohort studies of various race-ethnic groups. Methods and Results A prospective cohort of patients with AIS who were registered in a multicenter nationwide stroke registry (CRCS-K [Clinical Research Collaboration for Stroke in Korea] registry) was followed up for the occurrence of AMI through a linkage with the National Health Insurance Service claims database. The 5-year cumulative incidence and annual risk were estimated according to predefined demographic subgroups, stroke subtypes, a history of coronary heart disease (CHD), and known risk factors of CHD. A total of 11 720 patients with AIS were studied. The 5-year cumulative incidence of AMI was 2.0%. The annual risk was highest in the first year after the index event (1.1%), followed by a much lower annual risk in the second to fifth years (between 0.16% and 0.27%). Among subgroups, annual risk in the first year was highest in those with a history of CHD (4.1%) compared with those without a history of CHD (0.8%). The small-vessel occlusion subtype had a much lower incidence (0.8%) compared with large-vessel occlusion (2.2%) or cardioembolism (2.4%) subtypes. In the multivariable analysis, history of CHD (hazard ratio, 2.84; 95% CI, 2.01-3.93) was the strongest independent predictor of AMI after AIS. Conclusions The incidence of AMI after AIS in South Korea was relatively low and unexpectedly highest during the first year after stroke. CHD was the most substantial risk factor for AMI after stroke and conferred an approximate 5-fold greater risk.

Indexed as

Arterial Occlusive DiseasesIschemic StrokeMyocardial InfarctionRisk AssessmentAgedFemaleHeart Disease Risk FactorsHumansIncidenceMalePrognosisProspective StudiesRegistriesRepublic of Koreaacute ischemic strokeacute myocardial infarctioncoronary heart diseaseprospective cohort studyrisk factors

Identifiers

PMID33372531
PMCPMC7955456
OpenAlexW3116785596

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.