Evidence map›Paper›PMID 33372377›Full record

SynthesisClinical physiology and functional imaging2021

Prognostic value of left atrial volume index in acute coronary syndrome: A systematic review and meta-analysis.

Artan Ahmeti, Feriz S Bytyçi, Agata Bielecka-Dabrowa, Ibadete Bytyçi, Michael Y Henein

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Clinical physiology and functional imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07263282 (Left Atrium Strain as a Predictor of In-Hospital Outcomes in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07263282 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Left Atrium Strain as a Predictor of In-Hospital Outcomes in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

TypeobservationalSponsorAssiut UniversityRan2025 to 2027Enrolled135ConditionsST Elevation (STEMI) Myocardial InfarctionArms2D echocardiography
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Artan AhmetiClinic of Cardiology, University Clinical Centre of Kosovo, Prishtina, Kosovo.
Feriz S BytyçiMain Family Medical Center, Prishtina, Kosovo.
Agata Bielecka-DabrowaDepartment of Hypertension, Medical University of Lodz, Lodz, Poland.
Ibadete BytyçiClinic of Cardiology, University Clinical Centre of Kosovo, Prishtina, Kosovo.ORCID https://orcid.org/0000-0002-8996-4257
Michael Y HeneinInstitute of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
University Clinical Center of Kosovo · XKMedical University of Lodz · PLSt George's, University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the absence of mitral valve disease, increased left atrial volume (LAV) is a marker of diastolic dysfunction and long-standing elevated left ventricle (LV) pressure. The aim of this study was to assess the role of increased baseline LAV in predicting clinical outcome of patients presenting with acute coronary syndrome (ACS).

methodsWe systematically searched all electronic databases up to September 2020 in order to select clinical trials and observational studies, which assessed the predictive role of LAV indexed (LAVI) on clinical outcome in patients with ACS. Primary clinical endpoints were as follows: major adverse cardiac events (MACE), all-cause mortality and hospitalization. Secondary endpoints were in-hospital complications.

resultsA total of 2,705 patients from 11 cohort studies with a mean follow-up 18.7 ± 9.8 months were included in the meta-analysis. Patients with low LAVI had low risk for MACE (15.9% vs. 33.7%; p < .01), long-term all-cause mortality (9.14% vs. 18.1%; p < .01), short-term mortality (3.31% vs. 9.38%; p = .02) and lower hospitalization rate (11.6% vs. 25.5%; p < .01) compared to patients with increased LAVI. Atrial fibrillation and cardiogenic shock as in-hospital events were lower (p < .05 for all) in patients with low LAVI but ventricular fibrillation/tachycardia was not different between groups (p = .14).

conclusionIncreased LAVI is an independent predictor of outcome in patients with ACS. Thus, assessment of LA index in these patients is important for better risk stratification and guidance towards optimum clinical management.

Indexed as

Acute Coronary SyndromeAtrial FibrillationHeart AtriaHumansPrognosisRisk Factorsacute coronary syndromeclinical outcomeleft atrial volume

Identifiers

PMID33372377
PMCPMC7898886
OpenAlexW3115537906

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.