Evidence map›Paper›PMID 33372249›Full record

ArticleHistochemistry and cell biology2021

A comparison of airway pressures for inflation fixation of developing mouse lungs for stereological analyses.

David Pérez-Bravo, Despoina Myti, Ivana Mižíková, Tilman Pfeffer, David E Surate Solaligue, Claudio Nardiello, István Vadász, Susanne Herold, Werner Seeger, Katrin Ahlbrecht and 1 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Histochemistry and cell biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. AlveolEye: rapid and precise lung morphometry guided by computer vision.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
  2. Review
  3. Article
  4. Introduction: 3D imaging in lung biology.Histochemistry and cell biology · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

David Pérez-BravoDepartment of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Parkstrasse 1, 60231, Bad Nauheim, Germany.ORCID http://orcid.org/0000-0001-8105-7356
Despoina MytiDepartment of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Parkstrasse 1, 60231, Bad Nauheim, Germany.ORCID http://orcid.org/0000-0003-1810-7247
Ivana MižíkováDepartment of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Parkstrasse 1, 60231, Bad Nauheim, Germany.ORCID http://orcid.org/0000-0002-3440-9133
Tilman PfefferDepartment of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Parkstrasse 1, 60231, Bad Nauheim, Germany.
David E Surate SolaligueDepartment of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Parkstrasse 1, 60231, Bad Nauheim, Germany.ORCID http://orcid.org/0000-0002-3214-0468
Claudio NardielloDepartment of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Parkstrasse 1, 60231, Bad Nauheim, Germany.ORCID http://orcid.org/0000-0002-4287-6372
István VadászDepartment of Internal Medicine (Pulmonology), University of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Aulweg 123, 35394, Giessen, Germany.ORCID http://orcid.org/0000-0003-1370-9783
Susanne HeroldDepartment of Internal Medicine (Pulmonology), University of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Aulweg 123, 35394, Giessen, Germany.ORCID http://orcid.org/0000-0001-6343-0911
Werner SeegerDepartment of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Parkstrasse 1, 60231, Bad Nauheim, Germany.ORCID http://orcid.org/0000-0003-1946-0894
Katrin AhlbrechtDepartment of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Parkstrasse 1, 60231, Bad Nauheim, Germany.ORCID http://orcid.org/0000-0003-4200-3739
Rory E MortyDepartment of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Parkstrasse 1, 60231, Bad Nauheim, Germany. rory.morty@mpi-bn.mpg.de.ORCID http://orcid.org/0000-0003-0833-9749
Max Planck Institute for Heart and Lung Research · DEJustus-Liebig-Universität Gießen · DEHeidelberg University · DEUniversity of Ottawa · CA

Funding

Bundesministerium für Bildung und Forschung DZL-UGMLCDeutsche Forschungsgemeinschaft 160966624Deutsche Forschungsgemeinschaft 268555672Deutsche Forschungsgemeinschaft 284237345Deutsche Forschungsgemeinschaft 390649896Deutsche Forschungsgemeinschaft 420759458Max-Planck-Gesellschaft MPI-HLR
6 · The paper itself

Abstract

The morphometric analysis of lung structure using the principles of stereology has emerged as a powerful tool to describe the structural changes in lung architecture that accompany the development of lung disease that is experimentally modelled in adult mice. These stereological principles are now being applied to the study of the evolution of the lung architecture over the course of prenatal and postnatal lung development in mouse neonates and adolescents. The immature lung is structurally and functionally distinct from the adult lung, and has a smaller volume than does the adult lung. These differences have raised concerns about whether the inflation fixation of neonatal mouse lungs with the airway pressure (P

Indexed as

PressureAnimalsLungMiceMice, Inbred C57BLAirway pressureInflation fixationLung developmentLung volumeMouseStereology

Identifiers

PMID33372249
PMCPMC7910376
OpenAlexW3117949769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.